Protein Alignment CG5245 and Zfp879

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_775563.1
• Gene: Zfp879 / 214779
• MGIID: 3053099
• Length: 563
• Species: Mus musculus
• Alignment Length: 556
• Identity: 183/556 - (32%)
• Similarity: 263/556 - (47%)
• Gaps: 81/556 - (14%)

  Fly     8 QRPVKDEPPQEDTFEEELIFISNSDFEELE-------SEIKIENFCS-------YGK-----DLE 53
            |.||        ||.:..:..|..::..|:       .|:.:||:.:       :.|     .||
Mouse    11 QEPV--------TFRDVAVSFSQDEWLHLDPAQRTLYREVMLENYSNLVSLGILFSKPKVIAQLE 67

  Fly    54 PVKGVP---------------SKLKTCKSKIAKKRPLRKQ-TDTFKCTQCQKTFTRKENLE---- 98
            ..:..|               |..:...||...|:.|:.| .|.|......||...:|.||
Mouse    68 QAEDFPMVESGMFQGVYLGWKSLFEPIVSKEENKKVLKNQRVDKFFNFILGKTCVNEEQLEEQPG 132

  Fly    99 ------SHLRLHA-----EERPFECSHCSKSFGRRTHYKR-----------HLLKHE-------- 133
                  |.:.|..     :||.|......::.|.:..::|           ||.::.
Mouse   133 NKKNPFSEMLLSVRRGCRQERGFPGVGLVRNPGIKLPFRRKPGVAAGGGKPHLQQYSVLFKQLGF 197

  Fly   134 ---KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFEC 195
               ::..||:.|.|.|..:|||.:|...||||:.:||..|..:|:::|.|..|||.|:.|:|:.|
Mouse   198 NRARQLCKCNICGKVFFHSSSLSKHQRTHTGEKLYKCQGCRKAFSQRSSLAQHLRVHTGEKPYLC 262

  Fly   196 THCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCPKTFLQ 259
            :.|.|||...:.|..|.|.|...||::|..|.|:||..|.|..|...| .|:.:||.:|.:.|.|
Mouse   263 SDCGKAFSFTTSLIGHQRMHTGERPYECKECGKTFKGSSSLHNHQRIHTGEKPYKCNECGRAFSQ 327

  Fly   260 NDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVR 324
            ..||..|.|:|.||.|::|..|.:.|...|||..|...|.|::|..|:.|...|:..|...:|.|
Mouse   328 CSSLIQHHRIHTGEKPYECSQCGKAFTSISRLSRHHRVHTGEKPFHCNVCGKVFSYHSALTIHQR 392

  Fly   325 LHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPK 389
            .||.|:.|.|.||.|:|.:.|.|.:||::||||:|:||..|.|.|...:.|.:|...|.|||...
Mouse   393 THTGEKPYACKECGKAFSQSSALTQHQRIHTGEKPYKCAECGKAFSWLSRLNIHHRIHTGEKPYH 457

  Fly   390 CSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFA 454
            |..|.|.|...|.:..|.:.|||:..::|..|.|::..||.|..|.|.||||.||.|..|.|.|.
Mouse   458 CKECGKAFSSHSAVNTHRKIHTGEKPYKCSDCEKAFNQSSALIQHQRIHTGEKPFNCKVCGKAFR 522

  Fly   455 RSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            :|:....|:|.||||:||:|..|...::|.|||..|
Mouse   523 QSSSLMTHMRIHTGERPYRCEACGKAFSQSSSLANH 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	159/442 (36%)
		C2H2 Zn finger	84..104	CDD:275368	6/29 (21%)
		C2H2 Zn finger	112..132	CDD:275368	4/30 (13%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	9/19 (47%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	7/17 (41%)
Zfp879	NP_775563.1	KRAB	14..70	CDD:214630	11/63 (17%)
		COG5048	205..558	CDD:227381	146/352 (41%)
		C2H2 Zn finger	206..226	CDD:275368	8/19 (42%)
		C2H2 Zn finger	234..254	CDD:275368	8/19 (42%)
		C2H2 Zn finger	262..282	CDD:275368	8/19 (42%)
		C2H2 Zn finger	290..310	CDD:275368	8/19 (42%)
		C2H2 Zn finger	318..338	CDD:275368	8/19 (42%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		C2H2 Zn finger	374..394	CDD:275368	6/19 (32%)
		C2H2 Zn finger	402..422	CDD:275368	9/19 (47%)
		C2H2 Zn finger	430..450	CDD:275368	6/19 (32%)
		C2H2 Zn finger	458..478	CDD:275368	6/19 (32%)
		C2H2 Zn finger	486..506	CDD:275368	8/19 (42%)
		C2H2 Zn finger	514..534	CDD:275368	7/19 (37%)
		C2H2 Zn finger	542..562	CDD:275368	7/17 (41%)