Protein Alignment CG5245 and Zfp677

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_766074.2
• Gene: Zfp677 / 210503
• MGIID: 3053207
• Length: 634
• Species: Mus musculus
• Alignment Length: 505
• Identity: 182/505 - (36%)
• Similarity: 268/505 - (53%)
• Gaps: 38/505 - (7%)

  Fly     2 DLANVDQR---PVKDEPPQ----EDTF-------EEELIFISNSDFEELESEIKIENFCSYGKDL 52
            |..|.|:.   ...:||.:    |.||       :::.::.:..:..:.|.:   |:|.|..:.:
Mouse   113 DSPNADRHRSTHTGEEPYESKHCEKTFSLRSNISQDQRLYTAKKEHRQEEYD---EHFSSTHRLM 174

  Fly    53 EPVKGVPSKLKTCKSKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSK 117
            :.:..:..|                   ..:|.:|.|.|:...||..|.|:|..|:|::|:.|.|
Mouse   175 QQINYIGEK-------------------PHQCGKCGKCFSTSSNLTVHQRIHTGEKPYKCNLCDK 220

  Fly   118 SFGRRTHYKRHLLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQ 181
            ||.:.|..|.|...|. ::|:||..|..:|...||||.|.:.|.|.:|:||.:|..||..||.|.
Mouse   221 SFSQSTTLKTHQRLHTGEKPYKCRECGMSFPYLSSLKVHQNLHPGAKPYKCKECDKSFTIKSTLI 285

  Fly   182 VHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AE 245
            .|.|.|:.|:|:.|..|:::|:..::|:.|.|.|...:|:||..|.|:|...|.|:|||..| .:
Mouse   286 KHQRNHTGEKPYTCNVCDRSFRQCANLKTHQRLHTGEKPYKCKECGKAFTQSSSLKKHLNLHTGK 350

  Fly   246 RSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCS 310
            :.:||.:|.|:|.:..:|..|.|:|.|:.|:||..|.::|...:.|:.|...|.|::|.||.:|.
Mouse   351 KPYKCEECDKSFTEKSTLTTHKRIHTGKKPYKCNICGKSFNSCTNLKTHQTLHTGEKPYKCKECG 415

  Fly   311 ATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHL 375
            ..|...|..::|..||..|:.|||.||.|||..||.|..||.:||||:|:||..|.|.|...|:|
Mouse   416 KAFPYMSSLKIHQNLHPGEKPYKCKECDKSFTLKSSLRTHQIIHTGEKPYKCNICGKSFNQCTNL 480

  Fly   376 RVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTG 440
            :.|...|.|||..||..|.|.|...|.|..|...|:|:..::|..|.||:|..|||..|.|.|||
Mouse   481 KTHQRLHTGEKPYKCKECGKSFHYWSSLKSHQNLHSGEKPYKCKECDKSFTEKSTLIKHQRIHTG 545

  Fly   441 ELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            :..:||:.|.|.|...|..:.|.:.|||||||||..|...:.|.|:|.||
Mouse   546 KKLYKCNICDKSFTWCASLKTHKKFHTGEKPYKCRKCGKSFPQLSTLKRH 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	163/405 (40%)
		C2H2 Zn finger	84..104	CDD:275368	8/19 (42%)
		C2H2 Zn finger	112..132	CDD:275368	8/19 (42%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	6/19 (32%)
		C2H2 Zn finger	223..243	CDD:275368	9/19 (47%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		C2H2 Zn finger	334..354	CDD:275368	11/19 (58%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	10/19 (53%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	7/17 (41%)
Zfp677	NP_766074.2	KRAB	12..52	CDD:460171
		C2H2 Zn finger	104..124	CDD:275368	3/10 (30%)
		C2H2 Zn finger	132..151	CDD:275368	3/18 (17%)
		COG5048	183..600	CDD:227381	170/432 (39%)
		C2H2 Zn finger	187..207	CDD:275368	8/19 (42%)
		C2H2 Zn finger	215..235	CDD:275368	8/19 (42%)
		C2H2 Zn finger	243..263	CDD:275368	8/19 (42%)
		C2H2 Zn finger	271..291	CDD:275368	9/19 (47%)
		C2H2 Zn finger	299..319	CDD:275368	6/19 (32%)
		C2H2 Zn finger	327..347	CDD:275368	9/19 (47%)
		C2H2 Zn finger	355..375	CDD:275368	7/19 (37%)
		C2H2 Zn finger	383..403	CDD:275368	5/19 (26%)
		C2H2 Zn finger	411..431	CDD:275368	5/19 (26%)
		C2H2 Zn finger	439..459	CDD:275368	11/19 (58%)
		C2H2 Zn finger	467..487	CDD:275368	7/19 (37%)
		C2H2 Zn finger	495..515	CDD:275368	7/19 (37%)
		C2H2 Zn finger	523..543	CDD:275368	10/19 (53%)
		C2H2 Zn finger	551..571	CDD:275368	6/19 (32%)
		C2H2 Zn finger	579..599	CDD:275368	7/17 (41%)
		C2H2 Zn finger	612..632	CDD:275368