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Protein Alignment CG5245 and ZNF585A

DIOPT Version :9

Sequence 1:	NP_650197.1	Gene:	CG5245 / 41530	FlyBaseID:	FBgn0038047	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001275729.1	Gene:	ZNF585A / 199704	HGNCID:	26305	Length:	769	Species:	Homo sapiens

Alignment Length:	526	Identity:	178/526 - (33%)
Similarity:	264/526 - (50%)	Gaps:	78/526 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 SYGKDLEPVKGVPSKLKT---------CKSKIAKKRPLRKQTD------TFKCTQCQKTFTRKEN 96
            ||..||    .:..|:.|         |.....:|..|:....      ::.|.:|.:.|.:|.:
Human   224 SYNSDL----SIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTH 284

  Fly    97 LESHLRLHAEERPFECSHCSKSF------------------------------------------ 119
            |.:|.|:|..|:|:|||:|.|||
Human   285 LIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQS 349

  Fly   120 ----------GRRTHYKRHLLKHEK-----RPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQ 169
                      |:...|:..|:.|::     :|::||.|.|.|||.|:|..|...||||:.:.|.:
Human   350 REKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMK 414

  Fly   170 CSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRS 234
            |..:|.:|:||..|...|:.|:|.:|.||.|.|.:.|.|..|.|.|...:|:.|:.|.|:|..||
Human   415 CGLAFIQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRS 479

  Fly   235 ILQKHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEH 298
            .|..|..|| .|:|:.|::|.|.|.|...|..|.|:|.||.|::|..|.:.|.:.|.|.:|...|
Human   480 NLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQKIH 544

  Fly   299 AGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCT 363
            .|:...:|.:|...|..:|:..||.::||.|:.|.|.||.::|.:||:.:.||::||||:|::|:
Human   545 TGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIHTGEKPYECS 609

  Fly   364 HCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTS 428
            .|.|.|..::.|.||...|.|||...|:.|.|.|...|.|..|.:.|||:..:.|..|.|::...
Human   610 DCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQK 674

  Fly   429 STLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRR 493
            |.|..|.|.||||.|::||.|.|.|.:.::.|.|.|.|||||||.|:.|...:|.:|:|.:| :.
Human   675 SELITHHRIHTGEKPYECSDCGKSFTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKH-QT 738

  Fly   494 TLCGTK 499
            |..|.|
Human   739 THTGDK 744

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.