DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5245 and Zfp3

DIOPT Version :9

Sequence 1:	NP_650197.1	Gene:	CG5245 / 41530	FlyBaseID:	FBgn0038047	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_808233.1	Gene:	Zfp3 / 193043	MGIID:	99177	Length:	497	Species:	Mus musculus

Alignment Length:	469	Identity:	167/469 - (35%)
Similarity:	242/469 - (51%)	Gaps:	50/469 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PQEDTFEEELIFISNSDFEELESEIKIEN----------FCSYGKDLEPVKGVPSKLKTCKSKI- 69
            |||..|...|:....|...|..|    ||          .|..|  .|......:....|...|
Mouse    64 PQERHFASGLLIFKKSSSGEKTS----ENPRGFNPNPSVLCHGG--AERASACAASGHNCLGSIE 122

  Fly    70 ---AKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLK 131
               |:..|:.::..|  |.:|.|.|.:..:|..|:|:|:.|:||||..|.|:||
Mouse   123 LTKAQGPPVGEKPHT--CKECGKAFNQNSHLIQHMRVHSGEKPFECKECGKTFG----------- 174

  Fly   132 HEKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECT 196
                            .||||::|...|.||:||.||:|..:|.:.|||..|.|.|:.|||::|.
Mouse   175 ----------------TNSSLRRHQRIHAGEKPFACTECGKAFIQSSHLIHHHRIHTGERPYKCE 223

  Fly   197 HCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTHA-ERSFKCTQCPKTFLQN 260
            .|.|||..||.|..|.|.|...:|::|:.|.|:|::.|.|.:|...|. ||..:|::|.|.|..:
Mouse   224 ECGKAFSQNSALILHQRIHTGEKPYECNECGKTFRVSSQLIQHQRIHTEERYHECSECGKAFKHS 288

  Fly   261 DSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRL 325
            ..|..|.::|.||.|:.|..|.:.|.::|.|..|...|.|.:|.:||:|..||...|....|:|:
Mouse   289 SGLIRHQKIHTGEKPYLCNECGKGFGQSSELIRHQRIHTGDKPYECSECGKTFGQNSEIIRHIRI 353

  Fly   326 HTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKC 390
            ||.|:.|.|.||.|:|...|.|:.|:::||||:|::|..|.|.|:..:||.||...|.|||..:|
Mouse   354 HTGEKPYVCKECGKAFRGNSELLRHERIHTGEKPYECFECGKAFRRTSHLIVHQRIHTGEKPHQC 418

  Fly   391 SYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFAR 455
            :.|::.|..:|:||:|.:.|.|:..:||..|.|:::..|.|.:|.|.||||.|::|..|.|.|:|
Mouse   419 NECARTFWDNSELLLHQKIHIGEKPYECSECEKTFSQHSQLTIHQRIHTGEKPYECQECQKTFSR 483

  Fly   456 SAEHQEHLRTHTGE 469
            |:....|...|..|
Mouse   484 SSHLLRHQSVHCSE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	151/397 (38%)
		C2H2 Zn finger	84..104	CDD:275368	7/19 (37%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	5/19 (26%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		zf-H2C2_2	179..204	CDD:290200	13/24 (54%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	8/19 (42%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	8/19 (42%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368
Zfp3	NP_808233.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53
		COG5048	134..494	CDD:227381	148/388 (38%)
		zf-C2H2	136..158	CDD:278523	8/23 (35%)
		C2H2 Zn finger	138..158	CDD:275368	7/19 (37%)
		zf-H2C2_2	150..175	CDD:290200	13/51 (25%)
		C2H2 Zn finger	166..186	CDD:275368	10/46 (22%)
		zf-H2C2_2	178..203	CDD:290200	12/24 (50%)
		C2H2 Zn finger	194..214	CDD:275368	9/19 (47%)
		zf-H2C2_2	206..231	CDD:290200	13/24 (54%)
		C2H2 Zn finger	222..242	CDD:275368	10/19 (53%)
		zf-H2C2_2	238..257	CDD:290200	7/18 (39%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		zf-H2C2_2	291..313	CDD:290200	8/21 (38%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		zf-H2C2_2	318..341	CDD:290200	8/22 (36%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		zf-H2C2_2	349..369	CDD:290200	10/19 (53%)
		C2H2 Zn finger	362..382	CDD:275368	8/19 (42%)
		zf-H2C2_2	374..399	CDD:290200	11/24 (46%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		zf-H2C2_2	430..455	CDD:290200	9/24 (38%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		zf-H2C2_2	459..483	CDD:290200	12/23 (52%)
		C2H2 Zn finger	474..494	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000