Protein Alignment CG5245 and Giot1

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_598247.1
• Gene: Giot1 / 171090
• RGDID: 620184
• Length: 654
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 163/479 - (34%)
• Similarity: 246/479 - (51%)
• Gaps: 45/479 - (9%)

  Fly    17 QEDTFEEEL---IFISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQ 78
            :|||:|..|   .|.|:|...:                                     || ..:
  Rat   203 EEDTYEYNLCDKAFRSDSSLHQ-------------------------------------RP-HLE 229

  Fly    79 TDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKHE-KRPHKCSHC 142
            ...:|..|.:|.|.....|:.| |.|..|:|::|:.|.|:|..|.:.|.|...|. ::|:.|:.|
  Rat   230 VAPYKYYQYEKDFAHHSCLQEH-RTHTGEKPYKCNQCGKAFASRHNLKMHERIHTGEKPYTCNQC 293

  Fly   143 SKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSH 207
            .|.||..::|::|...||||:|::|:||..:|||::.||||.|.|:.|:|:||:.|.|||.:.|:
  Rat   294 GKAFTLYTNLRKHEKIHTGEKPYECSQCGKAFARRNELQVHERIHTGEKPYECSQCGKAFASRSN 358

  Fly   208 LQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFKCTQCPKTFLQNDSLQIHLRVHA 271
            ||.|.|||...:|:.|:.|.|:|..|.:||.|...| .|:.:.|.||.|.|....||..|.::|.
  Rat   359 LQTHERTHTGEKPYLCNQCGKAFAWRRLLQIHERIHTGEKPYACNQCGKAFTHFPSLHNHKKIHT 423

  Fly   272 GEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAE 336
            ||.|:.|..|.:.||..:....|...|.|::|..|.||...|:.||..::|...|..|:.::|.:
  Rat   424 GEKPYTCNECGKAFAHLTSFHNHKKIHTGEKPYGCKQCGKAFSFRSNLQIHETAHKGEKPHECNQ 488

  Fly   337 CSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSS 401
            |.|:|....:|..|::.| |::|::|..|.|.|.....|:.|:..|.|||..:|:.|.|.|...:
  Rat   489 CGKAFAHIVYLQRHERSH-GDKPYECNQCGKGFTHFGRLKNHLKSHTGEKPYECNQCGKVFAYRN 552

  Fly   402 QLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTH 466
            .|..|.:.|||:..:.|..|.|::.:...|..|.:.||.|.|:.|:.|.|.||.....|.|.|.|
  Rat   553 NLQKHERTHTGEKPYVCDQCGKAFASRCNLQKHEKIHTQEKPYVCNQCGKAFASRCNFQVHERIH 617

  Fly   467 TGEKPYKCSHCSTRYTQKSSLGRH 490
            ||||.|..:.|...:..:|:|.:|
  Rat   618 TGEKSYSYNQCGKDFVSQSNLQKH 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	150/405 (37%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	11/19 (58%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	8/19 (42%)
		C2H2 Zn finger	278..298	CDD:275368	5/19 (26%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	5/19 (26%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..492	CDD:275368	4/17 (24%)
Giot1	NP_598247.1	KRAB	4..44	CDD:460171
		C2H2 Zn finger	131..151	CDD:275368
		C2H2 Zn finger	159..176	CDD:275368
		C2H2 Zn finger	182..201	CDD:275368
		COG5048	258..654	CDD:227381	144/385 (37%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	290..310	CDD:275368	7/19 (37%)
		C2H2 Zn finger	318..338	CDD:275368	11/19 (58%)
		C2H2 Zn finger	346..366	CDD:275368	10/19 (53%)
		C2H2 Zn finger	374..394	CDD:275368	8/19 (42%)
		C2H2 Zn finger	402..422	CDD:275368	8/19 (42%)
		C2H2 Zn finger	430..450	CDD:275368	5/19 (26%)
		C2H2 Zn finger	458..478	CDD:275368	7/19 (37%)
		C2H2 Zn finger	486..506	CDD:275368	6/19 (32%)
		C2H2 Zn finger	513..533	CDD:275368	6/19 (32%)
		C2H2 Zn finger	541..561	CDD:275368	6/19 (32%)
		C2H2 Zn finger	569..589	CDD:275368	5/19 (26%)
		C2H2 Zn finger	597..617	CDD:275368	8/19 (42%)
		C2H2 Zn finger	625..645	CDD:275368	4/17 (24%)