Protein Alignment CG5245 and Zfp483

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_596913.1
• Gene: Zfp483 / 170955
• RGDID: 727958
• Length: 733
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 167/573 - (29%)
• Similarity: 252/573 - (43%)
• Gaps: 102/573 - (17%)

  Fly    10 PVKDEPPQEDTFEEELIFISNSDFE-------ELESEIKIENFCSYGKDLEPVKGVP-------S 60
            |.:.||.:..|||:..:..:..:::       ||..|:.:||..|    || |.|.|       |
  Rat   167 PPRAEPREAVTFEDVSVDFTRGEWKLLEPSQRELYKEVLLENLGS----LE-VLGSPVSKFDLIS 226

  Fly    61 KLKTCKSKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHY 125
            .||..|.....::.|.|  |.......:::.:|.| |::.:.....|:..|.......:|.:|.:
  Rat   227 HLKWVKLPRVLEKELSK--DPRPGESVKESESRSE-LDAFMEELTLEKTVEYCFSGGGYGLKTEF 288

  Fly   126 KRHLLKHEK-----RPHKCSHC-------SKTFTQNSSLKQH---------LHEHTGERPF---- 165
            ::.|.|.||     :.|:....       .|...|.|::.:|         .....|::||
  Rat   289 QKRLGKPEKDHGRRKSHESKEAESGETTSEKNVKQTSAMLKHRKALLTKTSQRSKEGKKPFSFHS 353

  Fly   166 -----------KCTQCS----------TSFARKSHLQVHLRTHSEE---------RPFEC---TH 197
                       |..:||          :...||.|.::.....:|:         |...|   :.
  Rat   354 ALVNRRELSGGKSRKCSDREKDPHRPLSPTERKRHPKIGSLRKTEKCSKCGVDFTRILGCVESSQ 418

  Fly   198 CEKAFKNNSHLQEHLRTHQEA---RPFKCSHCSKSFKL---RSILQKHLLTH------------- 243
            |||. :.|....|.....|||   .|.||..|.|:.:.   ||:..:....|
  Rat   419 CEKC-RKNLFQDETSSKDQEADTEEPRKCKKCGKALEYGSKRSVCVECRNAHKASPSLKPQGKTD 482

  Fly   244 -AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCS 307
             .::|:||.:|.|.|.:.:....|.|.|..|.|:.|.||...|:.||....|...|.|::|..|.
  Rat   483 RRKKSYKCDECGKRFAEENDFSQHQRTHTREKPYVCKHCGRAFSDNSSFCQHQRIHTGEKPYTCK 547

  Fly   308 QCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCR 372
            :|..:|...|....|.|:||.|:.|||.||.|:|.:.|.|..||::||||:||.|..|...|:..
  Rat   548 ECGKSFTHSSSLSKHQRIHTGEKPYKCKECGKAFRQNSCLTRHQKIHTGEKPFLCKECGLSFRLF 612

  Fly   373 THLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRT 437
            :.:..|...|.|||..||.:|.|.|...|:|..||:.|||...::|..|.|::..||:|::|:||
  Rat   613 SSIMYHQRLHKGEKPYKCPHCEKGFPSHSRLSRHLRIHTGAKPYKCKECGKTFRQSSSLNLHIRT 677

  Fly   438 HTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            ||||.|:||::|...|.||....||::|||..| |.|..|...:..:|:..||
  Rat   678 HTGEKPYKCNYCGAAFTRSTILVEHVKTHTRVK-YDCKKCGKSFKSRSANLRH 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	142/481 (30%)
		C2H2 Zn finger	84..104	CDD:275368	3/19 (16%)
		C2H2 Zn finger	112..132	CDD:275368	3/19 (16%)
		C2H2 Zn finger	139..159	CDD:275368	4/35 (11%)
		C2H2 Zn finger	167..187	CDD:275368	5/29 (17%)
		C2H2 Zn finger	195..215	CDD:275368	6/22 (27%)
		C2H2 Zn finger	223..243	CDD:275368	5/22 (23%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	9/19 (47%)
		C2H2 Zn finger	362..382	CDD:275368	4/19 (21%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Zfp483	NP_596913.1	SCAN	45..133	CDD:460417
		KRAB	176..229	CDD:214630	15/57 (26%)
		COG5048	<487..730	CDD:227381	99/244 (41%)
		C2H2 Zn finger	490..510	CDD:275368	6/19 (32%)
		C2H2 Zn finger	518..538	CDD:275368	7/19 (37%)
		C2H2 Zn finger	546..566	CDD:275368	6/19 (32%)
		C2H2 Zn finger	574..594	CDD:275368	9/19 (47%)
		C2H2 Zn finger	602..622	CDD:275368	4/19 (21%)
		C2H2 Zn finger	630..650	CDD:275368	8/19 (42%)
		C2H2 Zn finger	658..678	CDD:275368	8/19 (42%)
		C2H2 Zn finger	686..706	CDD:275368	7/19 (37%)
		C2H2 Zn finger	713..730	CDD:275368	5/17 (29%)