Protein Alignment CG5245 and ZNF791

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_699189.2
• Gene: ZNF791 / 163049
• HGNCID: 26895
• Length: 576
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 184/510 - (36%)
• Similarity: 279/510 - (54%)
• Gaps: 23/510 - (4%)

  Fly     2 DLANVDQRPVKDEPPQEDTFEEELIFISNSDFEEL----ESEIKIENF---CSYGKDLEPVKGVP 59
            :||::.::  .::|..||..:.:...:.:...|.|    |.....|||   .|..|....||  |
Human    39 NLASIGEK--WEDPNVEDQHKNQGRNLRSHTGERLCEGKEGSQCAENFSPNLSVTKKTAGVK--P 99

  Fly    60 SKLKTCKSKIAK----KRPLRKQT------DTFKCTQCQKTFTRKENLESHLRLHAEERPFECSH 114
            .:...|.....:    .|.:|..|      ..:||.:|:|.|:..::.:.|.|.|..|:|::|..
Human   100 YECTICGKAFMRLSSLTRHMRSHTGYELFEKPYKCKECEKAFSYLKSFQRHERSHTGEKPYKCKQ 164

  Fly   115 CSKSFGRRTHYKRHLLKH-EKRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKS 178
            |.|:|.....::||...| .::|::|..|.|..:.:|||:.|...||||:|::|.||..:|:..|
Human   165 CGKTFIYHQPFQRHERTHIGEKPYECKQCGKALSCSSSLRVHERIHTGEKPYECKQCGKAFSCSS 229

  Fly   179 HLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH 243
            .::||.|||:.|:|:.|..|.|||.:::.:..|:.||...||:||..|.|:|...|.|:.|...|
Human   230 SIRVHERTHTGEKPYACKECGKAFISHTSVLTHMITHNGDRPYKCKECGKAFIFPSFLRVHERIH 294

  Fly   244 -AERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCS 307
             .|:.:||.||.|.|..:.|:|||.|:|.||.|:||..|.::|:.....::|:..|.|::|.||.
Human   295 TGEKPYKCKQCGKAFRCSTSIQIHERIHTGEKPYKCKECGKSFSARPAFRVHVRVHTGEKPYKCK 359

  Fly   308 QCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCR 372
            :|...|:..|.:|:|.|.||.|:.|:|.:|.|:|.....|..|::.||||:|::|..|.|.|...
Human   360 ECGKAFSRISYFRIHERTHTGEKPYECKKCGKTFNYPLDLKIHKRNHTGEKPYECKECAKTFISL 424

  Fly   373 THLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRT 437
            .:.|.||:.|.|:...||..|.|.|...|.|..|.:.|||:..:||..|.|:::.||.:.:|.||
Human   425 ENFRRHMITHTGDGPYKCRDCGKVFIFPSALRTHERTHTGEKPYECKQCGKAFSCSSYIRIHKRT 489

  Fly   438 HTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLR 492
            ||||.|::|..|.|.|......|.|:|.|||||||||..|...::..||..||.|
Human   490 HTGEKPYECKECGKAFIYPTSFQGHMRMHTGEKPYKCKECGKAFSLHSSFQRHTR 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	160/411 (39%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		C2H2 Zn finger	112..132	CDD:275368	6/19 (32%)
		C2H2 Zn finger	139..159	CDD:275368	7/19 (37%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	6/19 (32%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	10/19 (53%)
		C2H2 Zn finger	278..298	CDD:275368	4/19 (21%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
ZNF791	NP_699189.2	KRAB	3..44	CDD:460171	2/4 (50%)
		COG5048	98..573	CDD:227381	170/449 (38%)
		C2H2 Zn finger	102..122	CDD:275368	3/19 (16%)
		C2H2 Zn finger	134..154	CDD:275368	6/19 (32%)
		C2H2 Zn finger	162..182	CDD:275368	6/19 (32%)
		C2H2 Zn finger	190..210	CDD:275368	7/19 (37%)
		C2H2 Zn finger	218..238	CDD:275368	8/19 (42%)
		C2H2 Zn finger	246..266	CDD:275368	6/19 (32%)
		C2H2 Zn finger	274..294	CDD:275368	7/19 (37%)
		C2H2 Zn finger	302..322	CDD:275368	10/19 (53%)
		C2H2 Zn finger	330..350	CDD:275368	4/19 (21%)
		C2H2 Zn finger	358..378	CDD:275368	7/19 (37%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		C2H2 Zn finger	414..434	CDD:275368	7/19 (37%)
		C2H2 Zn finger	442..462	CDD:275368	7/19 (37%)
		C2H2 Zn finger	470..490	CDD:275368	7/19 (37%)
		C2H2 Zn finger	498..518	CDD:275368	7/19 (37%)
		C2H2 Zn finger	526..546	CDD:275368	7/19 (37%)
		C2H2 Zn finger	554..574	CDD:275368