Protein Alignment CG5245 and ZNF98

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001092096.1
• Gene: ZNF98 / 148198
• HGNCID: 13174
• Length: 572
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 173/520 - (33%)
• Similarity: 263/520 - (50%)
• Gaps: 45/520 - (8%)

  Fly     5 NVDQRPVKDEPP---------------QEDTFEEELIFISNSDFEELESE-IKIENFCSYGKDLE 53
            ||.:..:..|||               :::.|::.::    ..:::...| :::..:|   |.::
Human    73 NVKRHEMVTEPPVVYSYFAQDLWPKQGKKNYFQKVIL----RTYKKCGRENLQLRKYC---KSMD 130

  Fly    54 PVK-------GVPSKLKTCKSKIAKKRPLRKQTDTFKCTQCQKTFTRKENLESHLRLHAEERPFE 111
            ..|       |:...|.|.::||            |:..:..|.|.:..|...|...|..::.|:
Human   131 ECKVHKECYNGLNQCLTTTQNKI------------FQYDKYVKVFHKFSNSNRHKIGHTGKKSFK 183

  Fly   112 CSHCSKSFGRRTHYKRHLLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFA 175
            |..|.|||...:|..:|...|. ::|:||..|.|.:.:.|:|..|...|||::|:||.:|..:|.
Human   184 CKECEKSFCMLSHLAQHKRIHSGEKPYKCKECGKAYNEASNLSTHKRIHTGKKPYKCEECGKAFN 248

  Fly   176 RKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHL 240
            |.|||..|...|:.::|::|..|.|||..:::|..|.|.|...:|:||..|.::|...|.|..|.
Human   249 RLSHLTTHKIIHTGKKPYKCEECGKAFNQSANLTTHKRIHTGEKPYKCEECGRAFSQSSTLTAHK 313

  Fly   241 LTHA-ERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPL 304
            :.|| |:.:||.:|.|.|.|:.:|..|..:|.||..:||..|.:.|:|.|.|..|...|:|::|.
Human   314 IIHAGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKFYKCEECGKAFSRLSHLTTHKRIHSGEKPY 378

  Fly   305 KCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDF 369
            ||.:|...|...|....|.|:|..|:.|||..|||:|.:.|||..|:::||||:|:||..|.|.|
Human   379 KCEECGKAFKQSSTLTTHKRIHAGEKFYKCEVCSKAFSRFSHLTTHKRIHTGEKPYKCEECGKAF 443

  Fly   370 KCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMH 434
            ...:.|..|.:.|.|||..||..|.|.|..||.|..|...|||:..::|..|.|::..||.|..|
Human   444 NLSSQLTTHKIIHTGEKPYKCEECGKAFNQSSTLSKHKVIHTGEKPYKCEECGKAFNQSSHLTTH 508

  Fly   435 LRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGTK 499
            ...||||.|:||..|.|.|..|:....|...|||||.||...|:......:.:.:: :|...|.|
Human   509 KMIHTGEKPYKCEECGKAFNNSSILNRHKMIHTGEKLYKPESCNNACDNIAKISKY-KRNCAGEK 572

  Fly   500  499
            Human   573  572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	154/405 (38%)
		C2H2 Zn finger	84..104	CDD:275368	4/19 (21%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		C2H2 Zn finger	167..187	CDD:275368	8/19 (42%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	6/19 (32%)
		C2H2 Zn finger	250..270	CDD:275368	7/19 (37%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	9/19 (47%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	7/19 (37%)
		C2H2 Zn finger	446..466	CDD:275368	6/19 (32%)
		C2H2 Zn finger	474..492	CDD:275368	1/17 (6%)
ZNF98	NP_001092096.1	KRAB	13..73	CDD:214630	173/520 (33%)
		C2H2 Zn finger	184..204	CDD:275368	7/19 (37%)
		zf-H2C2_2	196..220	CDD:463886	8/23 (35%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		COG5048	235..566	CDD:227381	129/331 (39%)
		C2H2 Zn finger	240..260	CDD:275368	8/19 (42%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	296..316	CDD:275368	6/19 (32%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..372	CDD:275368	7/19 (37%)
		C2H2 Zn finger	380..400	CDD:275368	6/19 (32%)
		C2H2 Zn finger	408..428	CDD:275368	9/19 (47%)
		C2H2 Zn finger	436..456	CDD:275368	6/19 (32%)
		C2H2 Zn finger	464..484	CDD:275368	8/19 (42%)
		C2H2 Zn finger	492..512	CDD:275368	7/19 (37%)
		C2H2 Zn finger	520..540	CDD:275368	6/19 (32%)