Protein Alignment CG5245 and ZNF605

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001158187.1
• Gene: ZNF605 / 100289635
• HGNCID: 28068
• Length: 672
• Species: Homo sapiens
• Alignment Length: 169
• Identity: 27/169 - (15%)
• Similarity: 54/169 - (31%)
• Gaps: 48/169 - (28%)

  Fly    33 ETVNAMTAEISPTVSYLLDRGCANDTEIIDHLLIDRALYYNKHKLPSPQVDVRIEMWVQEVTSVS 97
            |.:..|....||::.:       ||.|.|...|.|.:..:::.::.:...|:....:|.||.
Human   367 EKIEIMAPVTSPSLDF-------NDNEDIPTELSDSSDTHDEGEVQAFYEDLSGRQYVNEVF--- 421

  Fly    98 ELTQDFEIDLYMNEYWTDPGLAYDIL-----------------NPCQGNLSFDWAVMQNIWTPNT 145
                :|.:|...:..:|:.....|.:                 |..|..:......:.|...|.|
Human   422 ----NFSVDKLYDLLFTNSPFLRDFMEQRRFSDIIFHPWKKEENGNQSRVILYTITLTNPLAPKT 482

  Fly   146 -----------------CFINSKKAQLHSSPFTNVFLMV 167
                             |::...:...|..|:.:.|..:
Human   483 ATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	17/128 (13%)
		C2H2 Zn finger	84..104	CDD:275368	3/19 (16%)
		C2H2 Zn finger	112..132	CDD:275368	4/36 (11%)
		C2H2 Zn finger	139..159	CDD:275368	5/36 (14%)
		C2H2 Zn finger	167..187	CDD:275368	0/1 (0%)
		C2H2 Zn finger	195..215	CDD:275368
		C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	250..270	CDD:275368
		C2H2 Zn finger	278..298	CDD:275368
		C2H2 Zn finger	306..326	CDD:275368
		C2H2 Zn finger	334..354	CDD:275368
		C2H2 Zn finger	362..382	CDD:275368
		C2H2 Zn finger	390..410	CDD:275368
		C2H2 Zn finger	418..438	CDD:275368
		C2H2 Zn finger	446..466	CDD:275368
		C2H2 Zn finger	474..492	CDD:275368
ZNF605	NP_001158187.1	KRAB	7..65	CDD:214630
		C2H2 Zn finger	176..196	CDD:275368
		COG5048	199..603	CDD:227381	27/169 (16%)
		C2H2 Zn finger	202..222	CDD:275368
		C2H2 Zn finger	230..250	CDD:275368
		C2H2 Zn finger	258..278	CDD:275368
		C2H2 Zn finger	286..306	CDD:275368
		C2H2 Zn finger	314..334	CDD:275368
		C2H2 Zn finger	342..362	CDD:275368
		C2H2 Zn finger	370..390	CDD:275368	7/26 (27%)
		C2H2 Zn finger	398..418	CDD:275368	1/19 (5%)
		C2H2 Zn finger	426..446	CDD:275368	3/19 (16%)
		C2H2 Zn finger	454..474	CDD:275368	2/19 (11%)
		C2H2 Zn finger	482..502	CDD:275368	2/19 (11%)
		C2H2 Zn finger	510..530	CDD:275368	3/12 (25%)
		C2H2 Zn finger	538..558	CDD:275368
		C2H2 Zn finger	566..586	CDD:275368
		C2H2 Zn finger	594..614	CDD:275368
		zf-C2H2	620..642	CDD:395048
		C2H2 Zn finger	622..642	CDD:275368
		C2H2 Zn finger	650..670	CDD:275368