Protein Alignment CG5245 and Gm10778

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001136435.1
• Gene: Gm10778 / 100233208
• MGIID: 3809656
• Length: 499
• Species: Mus musculus
• Alignment Length: 501
• Identity: 180/501 - (35%)
• Similarity: 268/501 - (53%)
• Gaps: 49/501 - (9%)

  Fly    20 TFEEELIFISNSDFEELESEIKIENFCSYGKDLEPVKGVPSKLKTCKSKIAKKRPLRKQTDTFKC 84
            |:|:..:..::.::..|:...|     |..||:        .|:||::..|....|:.......|
Mouse     5 TYEDVYVKFTHEEWALLDPSQK-----SLYKDV--------MLETCRNLTAIGYKLQDDNIEEHC 56

  Fly    85 ------------------------TQCQKTFTRKENLESHLRLHAEERPFECSHCSKSFGRRTHY 125
                                    .||  ||.:|..|:::.|:.:||:|:||:.|||:|..
Mouse    57 PSSRGCGRYNIYGYKPCEHKGYGKKQC--TFAQKRFLQTYERICSEEKPYECNQCSKAFAN---- 115

  Fly   126 KRHLLKHEK-----RPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQVHLR 185
            .|.|.||||     :|::|:||.|.|...|:|:.|...||||:||.|::|..:|||.|:|.:|.|
Mouse   116 FRSLQKHEKNHTREKPYECNHCGKAFPSRSALQIHQRTHTGEKPFDCSECGKAFARHSNLDIHKR 180

  Fly   186 THSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AERSFK 249
            ||:.|:|::|..|.|||...||||.|...|...:|:.|:.|.|:|..||.|:.|..|| .|:.::
Mouse   181 THTGEKPYDCNECGKAFSTRSHLQIHEIIHTGEKPYVCNQCGKAFAYRSNLEAHEKTHTGEKPYE 245

  Fly   250 CTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCSATFA 314
            |.||...:....||:.|.:.|.||..:.|..|.:.|||.|.|::|...|.|::|..|:||...||
Mouse   246 CNQCGNVYASRSSLRNHEKHHTGEKLYGCNQCGKAFARRSSLEIHERTHTGEKPYVCNQCCKAFA 310

  Fly   315 MRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHM 379
            .||..::|.|.||.|:.|:|.:|.|:|..::.|..|::.||||:|:.|..|.|.|:.:..|::|.
Mouse   311 RRSSLQIHERSHTGEKPYECNQCGKAFASRTSLQNHEKHHTGEKPYGCNQCDKAFELKCDLQIHE 375

  Fly   380 LDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTGELPF 444
            ..|.|||...|:.|.|.|.....|..|.:.||.:..::|..|.||:.....|..|.:|||||.|:
Mouse   376 RIHTGEKPYVCNQCGKAFVSRRYLRNHEKHHTLEKLYDCSQCGKSFAIFRYLQKHKKTHTGEKPY 440

  Fly   445 KCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRH 490
            ||:||.|.||..:....|.|:|||||.|:|:.|...:...:||..|
Mouse   441 KCTHCGKAFAYRSNLYRHERSHTGEKLYECNECGKAFAYHTSLHNH 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	165/433 (38%)
		C2H2 Zn finger	84..104	CDD:275368	8/43 (19%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	10/19 (53%)
		C2H2 Zn finger	223..243	CDD:275368	8/19 (42%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	8/19 (42%)
		C2H2 Zn finger	306..326	CDD:275368	9/19 (47%)
		C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)
		C2H2 Zn finger	362..382	CDD:275368	6/19 (32%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	8/19 (42%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Gm10778	NP_001136435.1	KRAB	4..44	CDD:460171	11/51 (22%)
		COG5048	102..458	CDD:227381	145/359 (40%)
		C2H2 Zn finger	106..126	CDD:275368	11/23 (48%)
		C2H2 Zn finger	134..154	CDD:275368	8/19 (42%)
		C2H2 Zn finger	162..182	CDD:275368	9/19 (47%)
		C2H2 Zn finger	190..210	CDD:275368	10/19 (53%)
		C2H2 Zn finger	218..238	CDD:275368	8/19 (42%)
		C2H2 Zn finger	246..266	CDD:275368	6/19 (32%)
		C2H2 Zn finger	274..294	CDD:275368	8/19 (42%)
		C2H2 Zn finger	302..322	CDD:275368	9/19 (47%)
		C2H2 Zn finger	330..350	CDD:275368	6/19 (32%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
		C2H2 Zn finger	386..406	CDD:275368	6/19 (32%)
		C2H2 Zn finger	414..434	CDD:275368	6/19 (32%)
		C2H2 Zn finger	442..462	CDD:275368	8/19 (42%)
		zf-H2C2_2	454..479	CDD:463886	10/24 (42%)
		C2H2 Zn finger	470..490	CDD:275368	5/17 (29%)