Protein Alignment CG5245 and ZNF730

DIOPT Version :9

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_016881603.1
• Gene: ZNF730 / 100129543
• HGNCID: 32470
• Length: 514
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 155/463 - (33%)
• Similarity: 217/463 - (46%)
• Gaps: 60/463 - (12%)

  Fly    46 CSY-GKDLEPVKGVPS--------KLKTCKSKIAKKRPLRKQTDTFKC--------TQCQKTFTR 93
            ||: .:||.|.:|:..        :.|.|:.:....|...|..|.||.        .||..|
Human    89 CSHIAQDLWPEQGIKDYFQEVILRQYKKCRHENLLLRKGCKNVDEFKMHKKGYNRHNQCLTT--- 150

  Fly    94 KENLESHLRLHAEERPFECSHCSKSFGRRTHYKRHLLKH-EKRPHKCSHCSKTFTQNSSLKQHLH 157
                 ||.::      |:|....|.|.:.::..||.::| .|:|.||..|.|.|...|.|.||..
Human   151 -----SHSKI------FQCDKYVKVFHKFSNSNRHKIRHTSKKPFKCKECGKLFCILSHLAQHKK 204

  Fly   158 EHTGERPFKCTQCSTSFARKSHLQVHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFK 222
            .||||:.:||.:...:|...|:...|.|. :|::|::|..|.|||...||...|.|.|...:|::
Human   205 IHTGEKSYKCEEYGKAFNESSNCTTHKRI-TEKKPYKCKECGKAFNWFSHFTTHKRIHTGEKPYQ 268

  Fly   223 CSHCSKSFKLRSILQKHLLTHAERSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFAR 287
            |..|.|.|.                           |:.:|..|.|:|.||.|:||..|.:.|.:
Human   269 CEKCGKFFN---------------------------QSTNLTTHKRIHTGEKPYKCEECGKAFNQ 306

  Fly   288 NSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQ 352
            :|.|..|...|..::|.||.:|...|...|....|.|:|..|:.|||.||.|:|.:.|.|..|:.
Human   307 SSNLTEHKKIHTKEQPYKCEKCGKAFKWSSTLTKHKRIHNGEKPYKCEECGKAFNRSSTLNRHKI 371

  Fly   353 VHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFE 417
            .|||.:|:|...|.|.|...:.|.:|.:.|..||..||..|.|.|...|.|..|.:.|||:..::
Human   372 THTGGKPYKYKECGKAFNQSSTLTIHKIIHTVEKFYKCEECGKAFSRISHLTTHKRIHTGEKPYK 436

  Fly   418 CPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYT 482
            |..|.:::..||||..|.|.||||.|::|..|.|.|.||:....|...|:|||.|||..|...:.
Human   437 CEECGRAFNQSSTLTTHKRIHTGEKPYECEECGKAFNRSSTLTTHKIIHSGEKIYKCKECGKAFR 501

  Fly   483 QKSSLGRH 490
            :.|.|.||
Human   502 RFSHLTRH 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	141/412 (34%)
		C2H2 Zn finger	84..104	CDD:275368	5/27 (19%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	8/19 (42%)
		C2H2 Zn finger	167..187	CDD:275368	5/19 (26%)
		zf-H2C2_2	179..204	CDD:290200	9/24 (38%)
		C2H2 Zn finger	195..215	CDD:275368	9/19 (47%)
		C2H2 Zn finger	223..243	CDD:275368	4/19 (21%)
		C2H2 Zn finger	250..270	CDD:275368	4/19 (21%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	8/19 (42%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	6/17 (35%)
ZNF730	XP_016881603.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100020
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900