Protein Alignment CG5245 and Zfp850

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001241880.1
• Gene: Zfp850 / 100043772
• MGIID: 3036281
• Length: 689
• Species: Mus musculus
• Alignment Length: 471
• Identity: 161/471 - (34%)
• Similarity: 230/471 - (48%)
• Gaps: 37/471 - (7%)

  Fly    59 PSKLKTCKSKIAKKRPLRKQTDT------FKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSK 117
            |.:.|.|......::.|.:....      |:|.:|.|.|....:|..|..:||..:|:||:.|.|
Mouse   199 PYECKDCGKAFRLQQHLTRHQKAHSGERPFECNECGKFFKHGSSLVQHKIIHAGVKPYECNECGK 263

  Fly   118 SFGRRTHYKRHLLKH-EKRPHKCSHCSKTFTQNSSL-KQHLHEHTGERPFKCTQCSTSFARKSH- 179
            :|.||:::.||...| :|:|.:|..|...||..:.| .|..:.|.|::.|:|.||...|:..|:
Mouse   264 AFNRRSNFMRHQKVHYDKKPFQCKECGSAFTVLAQLITQPQNIHNGKKSFECKQCGKIFSNGSYH 328

  Fly   180 -----------------------LQV----HLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQE 217
                                   |||    |.:||::|:||:|..|...|:...||.||.|.|.:
Mouse   329 IQHQSIHSSEKAFGCHVCGKAFRLQVYLSEHQKTHTDEKPFKCNLCGSVFRRKYHLTEHQRIHTD 393

  Fly   218 ARPFKCSHCSKSFKLRSILQKHLLTHAE-RSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHC 281
            .:.::|..|.|.|:.||...:|...|.. :.|||..|...|.....|..|.|:|..|.|::|..|
Mouse   394 VKLYQCKECGKLFRRRSNFMEHQSIHTNVKPFKCELCGSAFRLQSLLSQHQRIHTDEKPYQCKEC 458

  Fly   282 SETFARNSRLQLHLLEHAGKEPLKCSQCSATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSH 346
            .:.|.|.|....||..|...:|.||..|.:.|.::||...|.|:||.|:.|:|.||.|.|.:.|:
Mouse   459 GKFFRRRSNFTEHLSIHTNVKPFKCELCGSAFRLQSLLNQHQRIHTGEKPYQCKECGKFFRRSSN 523

  Fly   347 LVEHQQVHTGERPFKCTHCFKDFKCRTHLRVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHT 411
            ..||:.:||..:||||..|...|:.::.|..|...|.|||..:|..|.|.|:..|....||..||
Mouse   524 FTEHRSIHTNVKPFKCELCGSAFRLQSLLSQHQRIHTGEKPYQCKECGKFFRRRSNFTEHLSIHT 588

  Fly   412 GKNQFECPHCSKSYTTSSTLHMHLRTHTGELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSH 476
            ....|:|..|...:...|.|:.|.|.||||.|::|..|.|.|.||:...|||..|||:||:.|:.
Mouse   589 NVKPFKCELCGSDFRLQSLLNQHQRIHTGEKPYQCKECGKFFRRSSNFTEHLSIHTGKKPFDCNK 653

  Fly   477 CSTRYTQKSSLGRHLR 492
            |...:.....|.||.|
Mouse   654 CGKVFRLNIHLIRHQR 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	153/440 (35%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		C2H2 Zn finger	112..132	CDD:275368	8/19 (42%)
		C2H2 Zn finger	139..159	CDD:275368	6/20 (30%)
		C2H2 Zn finger	167..187	CDD:275368	9/47 (19%)
		C2H2 Zn finger	195..215	CDD:275368	8/19 (42%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	6/19 (32%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	8/19 (42%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		C2H2 Zn finger	390..410	CDD:275368	7/19 (37%)
		C2H2 Zn finger	418..438	CDD:275368	6/19 (32%)
		C2H2 Zn finger	446..466	CDD:275368	9/19 (47%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Zfp850	NP_001241880.1	KRAB	14..75	CDD:214630
		C2H2 Zn finger	174..194	CDD:275368
		C2H2 Zn finger	202..222	CDD:275368	3/19 (16%)
		C2H2 Zn finger	230..250	CDD:275368	6/19 (32%)
		zf-C2H2	256..278	CDD:395048	9/21 (43%)
		C2H2 Zn finger	258..278	CDD:275368	8/19 (42%)
		COG5048	279..671	CDD:227381	137/391 (35%)
		C2H2 Zn finger	286..307	CDD:275368	6/20 (30%)
		C2H2 Zn finger	315..335	CDD:275368	5/19 (26%)
		C2H2 Zn finger	343..363	CDD:275368	4/19 (21%)
		C2H2 Zn finger	371..391	CDD:275368	8/19 (42%)
		C2H2 Zn finger	399..419	CDD:275368	7/19 (37%)
		C2H2 Zn finger	427..447	CDD:275368	6/19 (32%)
		C2H2 Zn finger	455..475	CDD:275368	7/19 (37%)
		C2H2 Zn finger	483..503	CDD:275368	7/19 (37%)
		C2H2 Zn finger	511..531	CDD:275368	8/19 (42%)
		C2H2 Zn finger	539..559	CDD:275368	5/19 (26%)
		C2H2 Zn finger	567..587	CDD:275368	7/19 (37%)
		C2H2 Zn finger	595..615	CDD:275368	6/19 (32%)
		C2H2 Zn finger	623..643	CDD:275368	9/19 (47%)
		C2H2 Zn finger	651..671	CDD:275368	6/19 (32%)