Protein Alignment CG5245 and Gm14399

DIOPT Version :10

• Sequence 1: NP_650197.1
• Gene: CG5245 / 41530
• FlyBaseID: FBgn0038047
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001375415.1
• Gene: Gm14399 / 100043761
• MGIID: 3650082
• Length: 610
• Species: Mus musculus
• Alignment Length: 449
• Identity: 178/449 - (39%)
• Similarity: 256/449 - (57%)
• Gaps: 9/449 - (2%)

  Fly    59 PSKLKTCKSKIAKKRPLRKQTDT------FKCTQCQKTFTRKENLESHLRLHAEERPFECSHCSK 117
            |...|.|....|:...||....|      ::|.||.|.|.|:.:|:.|.:.|..|:|:||:.|.|
Mouse   130 PYDCKQCGKAFARSCHLRMHNRTHAGEKQYECNQCGKAFKRRSDLQIHKQTHTGEKPYECNQCGK 194

  Fly   118 SFGRRTHYKRHLLKHE-KRPHKCSHCSKTFTQNSSLKQHLHEHTGERPFKCTQCSTSFARKSHLQ 181
            :|.|..|.:.|...|. ::|::|..|.|.|..:..|::|...||||:|::|.||..:|::.|||:
Mouse   195 AFARSCHLRIHKRTHTGEKPYECKQCGKAFVSSGDLQKHKRTHTGEKPYECKQCGKAFSQSSHLR 259

  Fly   182 VHLRTHSEERPFECTHCEKAFKNNSHLQEHLRTHQEARPFKCSHCSKSFKLRSILQKHLLTH-AE 245
            :|.|||:.|:|:||..|.|||..:..||:|.|||...:|::|..|.|:|...|.|..|...| .:
Mouse   260 IHKRTHTGEKPYECNQCGKAFARSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHIHERRHTGD 324

  Fly   246 RSFKCTQCPKTFLQNDSLQIHLRVHAGEDPFKCPHCSETFARNSRLQLHLLEHAGKEPLKCSQCS 310
            :.::|.||.|.|....:||:|.|.|.|:.|::|..|.:.|.....||:|...|.|::|.:|.||.
Mouse   325 KPYECKQCGKAFAVFYTLQMHKRTHTGDKPYECKQCGKAFTVIYTLQMHKQTHTGEKPYECKQCG 389

  Fly   311 ATFAMRSLYRVHVRLHTRERQYKCAECSKSFFKKSHLVEHQQVHTGERPFKCTHCFKDFKCRTHL 375
            ..|:.....|:|.|.||.|:.|:|.:|.|:|.:.....||::.||||:|::|..|.|.|..|..|
Mouse   390 KAFSQSRHLRIHKRTHTEEKPYECNQCGKAFARSGDQQEHKRTHTGEKPYECNQCGKAFIRRRVL 454

  Fly   376 RVHMLDHIGEKVPKCSYCSKEFKLSSQLLVHLQEHTGKNQFECPHCSKSYTTSSTLHMHLRTHTG 440
            ::|...|.|||..:|..|.|.|..||.|.:|.:.|||:..:||..|.|::..||||.:|.|||||
Mouse   455 QIHKRTHTGEKPYECKQCGKAFAGSSHLRIHKRTHTGQKPYECNQCGKAFAKSSTLQIHNRTHTG 519

  Fly   441 ELPFKCSHCSKLFARSAEHQEHLRTHTGEKPYKCSHCSTRYTQKSSLGRHLRRTLCGTK 499
            |.|::|..|.|.|......|.|.|||||||||:|..|...:...|.|.:| :||..|.|
Mouse   520 EKPYECYQCGKAFITRRVLQIHKRTHTGEKPYECKQCGKAFASSSDLQKH-KRTHSGEK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5245	NP_650197.1	COG5048	74..478	CDD:227381	166/411 (40%)
		C2H2 Zn finger	84..104	CDD:275368	8/19 (42%)
		C2H2 Zn finger	112..132	CDD:275368	7/19 (37%)
		C2H2 Zn finger	139..159	CDD:275368	6/19 (32%)
		C2H2 Zn finger	167..187	CDD:275368	9/19 (47%)
		C2H2 Zn finger	195..215	CDD:275368	9/19 (47%)
		C2H2 Zn finger	223..243	CDD:275368	7/19 (37%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		C2H2 Zn finger	278..298	CDD:275368	6/19 (32%)
		C2H2 Zn finger	306..326	CDD:275368	7/19 (37%)
		C2H2 Zn finger	334..354	CDD:275368	6/19 (32%)
		C2H2 Zn finger	362..382	CDD:275368	7/19 (37%)
		C2H2 Zn finger	390..410	CDD:275368	8/19 (42%)
		C2H2 Zn finger	418..438	CDD:275368	9/19 (47%)
		C2H2 Zn finger	446..466	CDD:275368	7/19 (37%)
		C2H2 Zn finger	474..492	CDD:275368	5/17 (29%)
Gm14399	NP_001375415.1	KRAB	3..44	CDD:460171
		COG5048	<53..199	CDD:227381	23/68 (34%)
		C2H2 Zn finger	79..97	CDD:275368
		C2H2 Zn finger	105..125	CDD:275368
		zf-H2C2_2	118..142	CDD:463886	3/11 (27%)
		C2H2 Zn finger	133..153	CDD:275368	5/19 (26%)
		C2H2 Zn finger	161..181	CDD:275368	8/19 (42%)
		COG5048	185..571	CDD:227381	157/386 (41%)
		C2H2 Zn finger	189..209	CDD:275368	7/19 (37%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	245..265	CDD:275368	9/19 (47%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
		C2H2 Zn finger	329..349	CDD:275368	9/19 (47%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		C2H2 Zn finger	413..433	CDD:275368	6/19 (32%)
		C2H2 Zn finger	441..461	CDD:275368	7/19 (37%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..517	CDD:275368	9/19 (47%)
		C2H2 Zn finger	525..545	CDD:275368	7/19 (37%)
		C2H2 Zn finger	553..573	CDD:275368	6/20 (30%)
		zf-H2C2_2	565..590	CDD:463886	6/14 (43%)
		C2H2 Zn finger	581..601	CDD:275368