DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5641 and zfr2

DIOPT Version :9

Sequence 1:	NP_650196.1	Gene:	CG5641 / 41529	FlyBaseID:	FBgn0038046	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_005161660.1	Gene:	zfr2 / 567465	ZFINID:	ZDB-GENE-070705-184	Length:	1004	Species:	Danio rerio

Alignment Length:	418	Identity:	96/418 - (22%)
Similarity:	177/418 - (42%)	Gaps:	77/418 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PMRGGIRPPFK-KTFVPRHPFDLTLAEVFFPKVPSAGAVDDSALTAALLKRNQDLSPTPSEQTAI 74
            |.|....||.. :..:|..|    |..|..|..|     ||..:.|    ::..:.|...|..|:
Zfish   625 PRRRMAPPPLMGRPSIPVPP----LLPVRRPDSP-----DDRHIMA----KHSAIYPVEEELQAV 676

  Fly    75 GNLVTKVQ--------AVLDNLVVAPGDLTTCQ---------LEEVRQVGSFKKGTILTGNNVAD 122
            ..:|:..:        .:|:.:..|..|.:...         |:.|.:||...||.:|.|:....
Zfish   677 QRIVSHSERALKLVSDTLLEKVACADDDESETDKQSETQSRTLKGVMRVGILAKGLLLRGDRNVQ 741

  Fly   123 VVVILKTLPTKEAVDALAKKVEADLKASMKTEVLTKGDQHTVQIHERGFDI---ANVHAKVRILI 184
            ::::....||...:..:|:::...|....:       ||:.||:|....:|   ::...|:::.|
Zfish   742 LILLAANKPTVSLLKTVAEQLPKQLATFSE-------DQYEVQVHPEEANIVIFSSKEPKMQVTI 799

  Fly   185 A-TLP-------QNLRKL---EPEIHLDHKLMQSHLAAIRHTRWFEENAHH-SSIKVLIRILKDL 237
            : |.|       .|:.|:   :|...|:......:|||:||.:||:..|:. .|..::||:|:||
Zfish   800 SLTSPVMREDPVPNMEKVSEKDPPDLLNRIKCLEYLAALRHAKWFQARANGLQSCVIIIRVLRDL 864

  Fly   238 TRRFDAFSPLSAWMLDLIAHLAIMNNPSRQALPIN--LAFRRVFQLLSAGLFLPGSAGITDPTEP 300
            .:|...:..:..|.::||...||    |..:.|::  .|.|||.:.::.|:.||...|:.||.|.
Zfish   865 CQRIPTWGKMPNWAMELIVEKAI----SSASGPLSPGEALRRVLECIATGILLPDGPGLLDPCEK 925

  Fly   301 GHIRVHTAMTLEQQDVCCYTSQTLLRVLAHGGYKHILGLEGNTSVVREMSVWNGVCISPLTAVYE 365
            |.......|:.:.::.....:|..||:||......:||: |:..|.:              |...
Zfish   926 GQTDALGTMSKQAREDVTANAQHALRLLAFRQIHKVLGM-GSLPVSK--------------AAAR 975

  Fly   366 KPTDKKEGDLEEDIDMIENENEEEGSDD 393
            ....:::|   .|:...|.:.:::..||
Zfish   976 NRKRRRDG---SDVGEGEADGKKDKKDD 1000

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5641	NP_650196.1	DZF	105..345	CDD:284860	67/256 (26%)
zfr2	XP_005161660.1	ZnF_U1	313..342	CDD:197732
		C2H2 Zn finger	315..337	CDD:275371
		ZnF_U1	358..392	CDD:197732
		C2H2 Zn finger	363..385	CDD:275371
		ZnF_U1	524..555	CDD:197732
		C2H2 Zn finger	527..549	CDD:275371
		DZF	718..968	CDD:128842	69/261 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3792
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810