DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5641 and zfr

DIOPT Version :9

Sequence 1:	NP_650196.1	Gene:	CG5641 / 41529	FlyBaseID:	FBgn0038046	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_012816329.1	Gene:	zfr / 496597	XenbaseID:	XB-GENE-6067390	Length:	1084	Species:	Xenopus tropicalis

Alignment Length:	420	Identity:	100/420 - (23%)
Similarity:	180/420 - (42%)	Gaps:	80/420 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GRPMRGGIRPPFKKTFVPRHPFDLTLAEVFFPKVPSAGAVDDSALTAALLKRNQDLSPTPSEQTA 73
            |.|...|:||...    |:            |:.||.....||:....::.::..:.||..|..|
Frog   705 GPPGLLGVRPGMP----PQ------------PQGPSPLRRPDSSDDRYVMTKHAAIYPTEEELQA 753

  Fly    74 IGNLVTKVQAVLDNLVVAPGDLTTCQLEE---------------VRQVGSFKKGTILTGNNVADV 123
            :..:|:..:..|..:..:..|....:.:|               |.:||...||.:|.|:....:
Frog   754 VQKIVSLTERALKLVSDSMADQDKSKTKESDDKKEPSKERALKGVLRVGVLAKGLLLRGDRNVSL 818

  Fly   124 VVILKTLPTKEAVDALAKKVEADLKASM------KTEVLTKGDQHTVQIHERGFDIANVHAKVRI 182
            |::....||:    ||..::...|...:      |.||.....:..:.::      :.|..|:::
Frog   819 VLLCAEKPTR----ALLSRITESLPKQLAVICPEKYEVSCSLAEAAIILN------SCVEPKMQV 873

  Fly   183 LIA-TLP----QNLR---------KLEPEIHLDHKLMQSHLAAIRHTRWFEENAHH-SSIKVLIR 232
            .|. |.|    :|||         |..|:: ||.:.....|||:||.:||:..|:. .|..::||
Frog   874 TITLTSPVIREENLRDGDVTPGMVKDPPDV-LDRQKCLDALAALRHAKWFQARANGLQSCVIIIR 937

  Fly   233 ILKDLTRRFDAFSPLSAWMLDLIAHLAIMNNPSRQALPINLAFRRVFQLLSAGLFLPGSAGITDP 297
            ||:||.:|...:|...:|.|:|:...||.::...|: |.: |.||||:.:|:|:.|.|..|:.||
Frog   938 ILRDLCQRVPTWSDFPSWALELLVEKAISSSSGPQS-PGD-ALRRVFECISSGIILKGGPGLLDP 1000

  Fly   298 TEPGHIRVHTAMTLEQQDVCCYTSQTLLRVLAHGGYKHILGLEGNTSVVREMSVWNGVCISPLTA 362
            .|.........|..:|::....::|..||:||......:||::..:.:.:..:|.|
Frog  1001 CEKDPYDTLATMNDQQREDITSSAQFALRLLAFRQIYKVLGMDPLSQMNQRFNVHN--------- 1056

  Fly   363 VYEKPTDKKEGDLEEDIDMIENENEEEGSD 392
                  ::|.....:.:|..|.|.:::..|
Frog  1057 ------NRKRRRDSDGVDSFEAEGKKDKKD 1080

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5641	NP_650196.1	DZF	105..345	CDD:284860	73/260 (28%)
zfr	XP_012816329.1	ZnF_U1	331..360	CDD:197732
		C2H2 Zn finger	333..355	CDD:275371
		ZnF_U1	384..413	CDD:197732
		C2H2 Zn finger	384..406	CDD:275371
		ZnF_U1	572..603	CDD:197732
		C2H2 Zn finger	575..597	CDD:275371
		DZF	794..1048	CDD:128842	74/266 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910