DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5641 and ilf2

DIOPT Version :9

Sequence 1:	NP_650196.1	Gene:	CG5641 / 41529	FlyBaseID:	FBgn0038046	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	NP_998401.1	Gene:	ilf2 / 406517	ZFINID:	ZDB-GENE-040426-2345	Length:	387	Species:	Danio rerio

Alignment Length:	395	Identity:	224/395 - (56%)
Similarity:	289/395 - (73%)	Gaps:	24/395 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RGALRGGR-PMRGGI----RPPFKKTFVPRHPFDLTLAEVFFPKVPSAGAVDDSALTAALLKRNQ 62
            ||..|||| ..|||:    ||     |||..|||..:.|:.||:|..|.  |::|.:..||||||
Zfish     5 RGRGRGGRFGSRGGLVQGYRP-----FVPHIPFDFYVCEMAFPRVKPAS--DETAFSECLLKRNQ 62

  Fly    63 DLSPTPSEQTAIGNLVTKVQAVLDNLVVAPGDLTTCQLEEVRQVGSFKKGTILTGNNVADVVVIL 127
            |||||||||.:|.:||||:..|:|||:||||:... |:||||||||:||||:..|:||||:||||
Zfish    63 DLSPTPSEQASILSLVTKINNVIDNLIVAPGNFEV-QIEEVRQVGSYKKGTMTAGHNVADLVVIL 126

  Fly   128 KTLPTKEAVDALAKKVEADLKASMKTEVLTKGDQHTVQIHERGFDIANVHAKVRILIATLPQNLR 192
            |.|||.|||.||..||...|:....:|||      ::..:|.||:|::..|.|:|||.|:|.|||
Zfish   127 KILPTLEAVAALGNKVVETLRTQDPSEVL------SMLTNETGFEISSADATVKILITTVPPNLR 185

  Fly   193 KLEPEIHLDHKLMQSHLAAIRHTRWFEENAHHSSIKVLIRILKDLTRRFDAFSPLSAWMLDLIAH 257
            ||:||:|||.|::||.||||||.|||||||..|::|||||:|||:..||..|.||:.|:|||:.|
Zfish   186 KLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKDIRVRFPGFEPLTPWILDLLGH 250

  Fly   258 LAIMNNPSRQALPINLAFRRVFQLLSAGLFLPGSAGITDPTEPGHIRVHTAMTLEQQDVCCYTSQ 322
            .|:||:||||.||:|:|:||..|:|:||||||||.|||||.|.|:.||||.|||||||:.|:|:|
Zfish   251 SAVMNHPSRQPLPLNVAYRRCLQMLAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCFTAQ 315

  Fly   323 TLLRVLAHGGYKHILGLEGNTS-VVREMSVWNGVCISPLTAVYEKPTDKKEGD---LEEDIDMIE 383
            ||:|||:||||:.||||||:.| :..|||.|:||.::|....||||.::||.:   |||.:: .|
Zfish   316 TLVRVLSHGGYRKILGLEGDASYLTTEMSTWDGVIVTPSEKAYEKPPERKEEEDEALEEGVE-AE 379

  Fly   384 NENEE 388
            :|:.|
Zfish   380 DESME 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5641	NP_650196.1	DZF	105..345	CDD:284860	148/240 (62%)
ilf2	NP_998401.1	DZF	98..338	CDD:128842	152/245 (62%)
ilf2	NP_998401.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	352..387		13/34 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589993
Domainoid	1	1.000	298	1.000	Domainoid score	I1423
eggNOG	1	0.900	-	-		E1_KOG3792
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H26894
Inparanoid	1	1.050	417	1.000	Inparanoid score	I1791
OMA	1	1.010	-	-		QHG48618
OrthoDB	1	1.010	-	-		D1145212at2759
OrthoFinder	1	1.000	-	-		FOG0006953
OrthoInspector	1	1.000	-	-		oto39102
orthoMCL	1	0.900	-	-		OOG6_107734
Panther	1	1.100	-	-	LDO	PTHR46447
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3592
SonicParanoid	1	1.000	-	-		X5046
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800