DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5641 and Ilf2

DIOPT Version :9

Sequence 1:	NP_650196.1	Gene:	CG5641 / 41529	FlyBaseID:	FBgn0038046	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_038958228.1	Gene:	Ilf2 / 310612	RGDID:	1305734	Length:	511	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	216/383 - (56%)
Similarity:	279/383 - (72%)	Gaps:	15/383 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GIRPPFKKTFVPRHPFDLTLAEVFFPKVPSAGAVDDSALTAALLKRNQDLSPTPSEQTAIGNLVT 79
            |.||     |||..|||..|.|:.||:|..  |.|:::.:.|||||||||:|..:||.:|.:|||
  Rat   143 GFRP-----FVPHIPFDFYLCEMAFPRVKP--APDETSFSEALLKRNQDLAPNSAEQASILSLVT 200

  Fly    80 KVQAVLDNLVVAPGDLTTCQLEEVRQVGSFKKGTILTGNNVADVVVILKTLPTKEAVDALAKKVE 144
            |:..|:|||:||||.... |:||||||||:||||:.||:||||:|||||.|||.|||.||..||.
  Rat   201 KINNVIDNLIVAPGTFEV-QIEEVRQVGSYKKGTMTTGHNVADLVVILKILPTLEAVAALGNKVV 264

  Fly   145 ADLKASMKTEVLTKGDQHTVQIHERGFDIANVHAKVRILIATLPQNLRKLEPEIHLDHKLMQSHL 209
            ..|:|...:|||      |:..:|.||:|::..|.|:|||.|:|.|||||:||:|||.|::||.|
  Rat   265 ESLRAQDPSEVL------TMLTNETGFEISSSDATVKILITTVPPNLRKLDPELHLDIKVLQSAL 323

  Fly   210 AAIRHTRWFEENAHHSSIKVLIRILKDLTRRFDAFSPLSAWMLDLIAHLAIMNNPSRQALPINLA 274
            |||||.|||||||..|::|||||:||||..||..|.||:.|:|||:.|.|:||||:||.|.:|:|
  Rat   324 AAIRHARWFEENASQSTVKVLIRLLKDLRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVA 388

  Fly   275 FRRVFQLLSAGLFLPGSAGITDPTEPGHIRVHTAMTLEQQDVCCYTSQTLLRVLAHGGYKHILGL 339
            :||..|:|:||||||||.|||||.|.|:.||||.|||||||:.|||:|||:|:|:|||::.|||.
  Rat   389 YRRCLQILAAGLFLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKILGQ 453

  Fly   340 EGNTS-VVREMSVWNGVCISPLTAVYEKPTDKKEGDLEEDIDMIENENEEEGSDDGAE 396
            ||:.| :..|:|.|:||.::|....||||.:||||:.||:......:.|||.|.:..|
  Rat   454 EGDASYLASEISTWDGVIVTPSEKAYEKPPEKKEGEEEEENTEEPPQGEEEESMETQE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5641	NP_650196.1	DZF	105..345	CDD:284860	149/240 (62%)
Ilf2	XP_038958228.1	DZF	219..459	CDD:128842	153/245 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348835
Domainoid	1	1.000	245	1.000	Domainoid score	I2118
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	347	1.000	Inparanoid score	I2239
OMA	1	1.010	-	-		QHG48618
OrthoDB	1	1.010	-	-		D1145212at2759
OrthoFinder	1	1.000	-	-		FOG0006953
OrthoInspector	1	1.000	-	-		oto95979
orthoMCL	1	0.900	-	-		OOG6_107734
Panther	1	1.100	-	-	LDO	PTHR46447
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5046
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910