DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5641 and AgaP_AGAP001997

DIOPT Version :9

Sequence 1:	NP_650196.1	Gene:	CG5641 / 41529	FlyBaseID:	FBgn0038046	Length:	396	Species:	Drosophila melanogaster
Sequence 2:	XP_321062.4	Gene:	AgaP_AGAP001997 / 1281124	VectorBaseID:	AGAP001997	Length:	398	Species:	Anopheles gambiae

Alignment Length:	392	Identity:	266/392 - (67%)
Similarity:	321/392 - (81%)	Gaps:	6/392 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVRGALRGGRPMRGGIR-PPF--KKTFVPRHPFDLTLAEVFFPKVPSAGAVDDSALTAALLKRNQ 62
            |:||..|||..|...:| .||  ||||:|||||||||||:.||:|..  |.|||.||.|||||:|
Mosquito     6 MMRGGGRGGMGMGMRVRGAPFMNKKTFLPRHPFDLTLAEMAFPRVQP--AQDDSVLTNALLKRSQ 68

  Fly    63 DLSPTPSEQTAIGNLVTKVQAVLDNLVVAPGDLTTCQLEEVRQVGSFKKGTILTGNNVADVVVIL 127
            ||:|..:|||||.|||:||||||||:|:||||.|.||||||||||||||||::.|:||||:|:||
Mosquito    69 DLTPAAAEQTAISNLVSKVQAVLDNIVIAPGDFTKCQLEEVRQVGSFKKGTMMAGSNVADIVIIL 133

  Fly   128 KTLPTKEAVDALAKKVEADLKASMKTEVLTKGDQHTVQIHERGFDIANVHAKVRILIATLPQNLR 192
            |:|||::..:||.||||.||:.||||||:...:..::...|:||:|:|..||||.||||||||:|
Mosquito   134 KSLPTRDCAEALGKKVEEDLEKSMKTEVVPTAEALSLSFSEKGFEISNSLAKVRCLIATLPQNMR 198

  Fly   193 KLEPEIHLDHKLMQSHLAAIRHTRWFEENAHHSSIKVLIRILKDLTRRFDAFSPLSAWMLDLIAH 257
            |||.|.|||.|::||||||||||||||||||||:|||||||||||.||||.|.||:.|:.||:||
Mosquito   199 KLETEKHLDFKIIQSHLAAIRHTRWFEENAHHSTIKVLIRILKDLARRFDGFKPLNPWICDLLAH 263

  Fly   258 LAIMNNPSRQALPINLAFRRVFQLLSAGLFLPGSAGITDPTEPGHIRVHTAMTLEQQDVCCYTSQ 322
            .||||||||||||:|:|||||||||::|||:|||||||||.|.||.||||:|||.|||.||.|:|
Mosquito   264 SAIMNNPSRQALPVNVAFRRVFQLLASGLFVPGSAGITDPCEVGHFRVHTSMTLVQQDECCMTAQ 328

  Fly   323 TLLRVLAHGGYKHILGLEGNTSVVREMSVWNGVCISPLTAVYEKPTDKKEGDLEEDIDMIENENE 387
            ||:|||||||||||||...||:|..|||||:||.:||:...||||::||:|: |:|::.:|.|..
Mosquito   329 TLVRVLAHGGYKHILGFVENTTVANEMSVWDGVVVSPMEPAYEKPSEKKDGE-EDDMECVEGETI 392

  Fly   388 EE 389
            .|
Mosquito   393 SE 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5641	NP_650196.1	DZF	105..345	CDD:284860	172/239 (72%)
AgaP_AGAP001997	XP_321062.4	DZF	111..351	CDD:284860	172/239 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	356	1.000	Domainoid score	I2703
eggNOG	1	0.900	-	-		E1_KOG3792
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H26894
Inparanoid	1	1.050	529	1.000	Inparanoid score	I2838
OMA	1	1.010	-	-		QHG48618
OrthoDB	1	1.010	-	-		D1145212at2759
OrthoFinder	1	1.000	-	-		FOG0006953
OrthoInspector	1	1.000	-	-		oto106560
Panther	1	1.100	-	-	LDO	PTHR46447
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5046
TreeFam	1	0.960	-	-
	13	12.940