Protein Alignment NANS and NANS

DIOPT Version :10

• Sequence 1: NP_650195.1
• Gene: NANS / 41528
• FlyBaseID: FBgn0038045
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_061819.2
• Gene: NANS / 54187
• HGNCID: 19237
• Length: 359
• Species: Homo sapiens
• Alignment Length: 357
• Identity: 168/357 - (47%)
• Similarity: 232/357 - (64%)
• Gaps: 24/357 - (6%)

  Fly    16 YIIAEIGQNHQGCVETAKKMIWEAKKAGCHCVKFQKSDLPAKFTRSALDREYISDHAWGKTYGEH 80
            :|||||||||||.::.||:||..||:.|..|.|||||:|..||.|.||:|.|.|.|:||||||||
Human    20 FIIAEIGQNHQGDLDVAKRMIRMAKECGADCAKFQKSELEFKFNRKALERPYTSKHSWGKTYGEH 84

  Fly    81 KEYLEFSKDQYLQLQAHCKELNVDFTASAMDERSLEFLSALNVPFIKIGSGDANNFPLLKKAANL 145
            |.:||||.|||.:||.:.:|:.:.||||.|||.::|||..|||||.|:||||.||||.|:|.|..
Human    85 KRHLEFSHDQYRELQRYAEEVGIFFTASGMDEMAVEFLHELNVPFFKVGSGDTNNFPYLEKTAKK 149

  Fly   146 NLPLVISTGMQTMQTVERIVQTMRESGKEDYALMHCVSSYPTDPKDCSLQLISVLRTRFPNVAIG 210
            ..|:|||:|||:|.|::::.|.::.. ..::..:.|.|:||..|:|.:|::||..:..||::.||
Human   150 GRPMVISSGMQSMDTMKQVYQIVKPL-NPNFCFLQCTSAYPLQPEDVNLRVISEYQKLFPDIPIG 213

  Fly   211 YSGHELGVIISQAAVLLGARIVERHFTLDKSQKGSDHRCSLEPQELKALTTAITNFKLSSVPMPP 275
            |||||.|:.||.|||.|||:::|||.||||:.|||||..||||.||..|..::
Human   214 YSGHETGIAISVAAVALGAKVLERHITLDKTWKGSDHSASLEPGELAELVRSV------------ 266

  Fly   276 QEIVKKLNGDEELEAALQHVESKTILPCELPCRNKLGKSIVAARNLNKGYRLQLADMAIKVSEPS 340
             .:|::..|.          .:|.:||||:.|..|||||:||...:.:|..|.:..:.:||.||.
Human   267 -RLVERALGS----------PTKQLLPCEMACNEKLGKSVVAKVKIPEGTILTMDMLTVKVGEPK 320

  Fly   341 GLTAEDFLDLVGKELADNIGEDEPILGNSIIN 372
            |...||..:||||::...:.||:.|:...:.|
Human   321 GYPPEDIFNLVGKKVLVTVEEDDTIMEELVDN 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NANS	NP_650195.1	SpsE	14..365	CDD:441692	166/348 (48%)
NANS	NP_061819.2	SpsE	17..351	CDD:441692	159/330 (48%)