DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scgbeta and SGCB

DIOPT Version :9

Sequence 1:	NP_524327.1	Gene:	Scgbeta / 41525	FlyBaseID:	FBgn0038042	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_000223.1	Gene:	SGCB / 6443	HGNCID:	10806	Length:	318	Species:	Homo sapiens

Alignment Length:	317	Identity:	85/317 - (26%)
Similarity:	143/317 - (45%)	Gaps:	86/317 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RLH-PGHQGRNTFAFWTIVVLLLVLTVGNLLLTLTIVGVLRLG-KGVQGMEVIPEVDLVKFYGTT 128
            ||| .|.:||.......:::||.:|.|.||::||.|..|:|:| .|...|| ..|..|::|
Human    51 RLHKTGLRGRKGNLAICVIILLFILAVINLIITLVIWAVIRIGPNGCDSME-FHESGLLRF---- 110

  Fly   129 DLERVQTNSIGQIHGFSDVPVTISSDAGDGEGGVHVRVFRNGNGAASERDRIVL---NREGILVQ 190
                .|.:.:|.||     |:..|:..|.          ||.|        :|:   |:..:..|
Human   111 ----KQVSDMGVIH-----PLYKSTVGGR----------RNEN--------LVITGNNQPIVFQQ 148

  Fly   191 ATNLFEVK---------------DPVDKQPIFTT--HRPQYNIPGGVEALQAKVVSASGIVSPID 238
            .|....|:               ||..:..:|:|  ...::::|.||::|..:..|...|.|...
Human   149 GTTKLSVENNKTSITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNAT 213

  Fly   239 ESLVLESDGRMAIRGSEGVYFDGASV--------DMQAEHHILINSTQGATILEAGTGIFLDMDR 295
            ..|.::.|||..:||:|||:..|.::        :::||:.|::|.:           :.:...|
Human   214 SDLNIKVDGRAIVRGNEGVFIMGKTIEFHMGGNMELKAENSIILNGS-----------VMVSTTR 267

  Fly   296 IPIVSSELGLRTGS---VQYKICVCMPHGTLFRIAIPRVHNGPKITCAHFSGKDDPC 349
            :|  ||..|.:.||   |:||:|:| ..||||::.:...:.|.:|:       |:||
Human   268 LP--SSSSGDQLGSGDWVRYKLCMC-ADGTLFKVQVTSQNMGCQIS-------DNPC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scgbeta	NP_524327.1	Sarcoglycan_1	73..330	CDD:282624	76/288 (26%)
SGCB	NP_000223.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
SGCB	NP_000223.1	Sarcoglycan_1	59..302	CDD:282624	76/288 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142511
Domainoid	1	1.000	78	1.000	Domainoid score	I8829
eggNOG	1	0.900	-	-		E1_28NAP
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5193
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49828
OrthoDB	1	1.010	-	-		D1214843at2759
OrthoFinder	1	1.000	-	-		FOG0007356
OrthoInspector	1	1.000	-	-		oto89903
orthoMCL	1	0.900	-	-		OOG6_108106
Panther	1	1.100	-	-	LDO	PTHR21142
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4347
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.800