DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Scgbeta and Sgcb

DIOPT Version :9

Sequence 1:	NP_524327.1	Gene:	Scgbeta / 41525	FlyBaseID:	FBgn0038042	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_036020.1	Gene:	Sgcb / 24051	MGIID:	1346523	Length:	320	Species:	Mus musculus

Alignment Length:	313	Identity:	87/313 - (27%)
Similarity:	143/313 - (45%)	Gaps:	78/313 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 RLH-PGHQGRNTFAFWTIVVLLLVLTVGNLLLTLTIVGVLRLG-KGVQGMEVIPEVDLVKFYGTT 128
            ||| .|.:||.......::|||.:|.|.|||:||.|..|:|:| .|...|| ..|..|::|
Mouse    53 RLHKTGLRGRKGNLAICVIVLLFILAVINLLITLVIWAVIRIGPNGCDSME-FHESGLLRF---- 112

  Fly   129 DLERVQTNSIGQIHGFSDVPVTISSDAGDGEGGVHVRVFRNGNGAASERDRIVLNREGILVQATN 193
                .|.:.:|.||     |:..|:..|.          ||.|...:..::.::.::|    .|.
Mouse   113 ----KQVSDMGVIH-----PLYKSTVGGR----------RNENLVITGNNQPIVFQQG----TTK 154

  Fly   194 LFEVK--------------DPVDKQPIFTT--HRPQYNIPGGVEALQAKVVSASGIVSPIDESLV 242
            |...|              ||.....:|:|  ...::::|.||::|..:..|...|.|.....|.
Mouse   155 LSVEKNKTSITSDIGMQFFDPRTHNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLN 219

  Fly   243 LESDGRMAIRGSEGVYF--------DGASVDMQAEHHILINSTQGATILEAGTGIFLDMDRIPIV 299
            ::.|||..:||:|||:.        .|..|:::||:.|::|.|           :.:...|:|
Mouse   220 IKVDGRAIVRGNEGVFIMGKTIEFHMGGDVELKAENSIILNGT-----------VMVSPTRLP-- 271

  Fly   300 SSELGLRTGS---VQYKICVCMPHGTLFRIAIPRVHNGPKITCAHFSGKDDPC 349
            ||..|.::||   |:||:|:| ..||||::.:...:.|.:::       |:||
Mouse   272 SSSSGDQSGSGDWVRYKLCMC-ADGTLFKVQVTGHNMGCQVS-------DNPC 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Scgbeta	NP_524327.1	Sarcoglycan_1	73..330	CDD:282624	79/284 (28%)
Sgcb	NP_036020.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
Sgcb	NP_036020.1	Sarcoglycan_1	61..302	CDD:282624	79/282 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832361
Domainoid	1	1.000	80	1.000	Domainoid score	I8627
eggNOG	1	0.900	-	-		E1_28NAP
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I5172
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49828
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007356
OrthoInspector	1	1.000	-	-		oto93480
orthoMCL	1	0.900	-	-		OOG6_108106
Panther	1	1.100	-	-	LDO	PTHR21142
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4347
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.790