DRSC/TRiP Functional Genomics Resources

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Protein Alignment pps and SET2

DIOPT Version :9

Sequence 1:NP_001247075.1 Gene:pps / 41524 FlyBaseID:FBgn0082831 Length:2018 Species:Drosophila melanogaster
Sequence 2:NP_012367.2 Gene:SET2 / 853271 SGDID:S000003704 Length:733 Species:Saccharomyces cerevisiae


Alignment Length:383 Identity:81/383 - (21%)
Similarity:142/383 - (37%) Gaps:82/383 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   954 KGI-DW--KCPKCVKRQEERSQPRITDMLVTRPTTQPEQRPSETKVLTTTAEIVQVAAPSAPRRT 1015
            ||| |:  :.||..:...|.||  |.:::.|.|...|..:|:..::|...::.      ...:|.
Yeast   401 KGILDFLLELPKTTRNGIESSQ--IDNVVKTLPAKFPFLKPNCDELLEKWSKF------ETYKRI 457

  Fly  1016 LPVVLTVASSPM------RIPMAKPAKKFPTGAISHQQQQQLNFIRLGPSPGKRISETLCVVCKR 1074
            ....:.||:|.|      |:|        |...|.|:..:.|.:          .:|....:...
Yeast   458 TKKDINVAASKMIDLRRVRLP--------PGWEIIHENGRPLYY----------NAEQKTKLHYP 504

  Fly  1075 PASTSSVYCGEECIRKYAQSAIQAHAATKGPLPQNAGAQSLLNNSFDAKKNKKKDLFEDVLRQAD 1139
            |:.:|.|:.        ::|..|.::.:...:|:..||       .|:||:|..|  |:..|:..
Yeast   505 PSGSSKVFS--------SRSNTQVNSPSSSGIPKTPGA-------LDSKKHKLSD--EEYERKKQ 552

  Fly  1140 TVSKVERINVFERKSGRVITGHMAPSAHQFRKWLQENPSFEVLPSGTVQSADAEKRLLKGAPEAA 1204
            ...:.|||.:...|...:      .|..|  |...||....|| ...:..|:.:|.|.|...:..
Yeast   553 KRLEYERIALERAKQEEL------ESLKQ--KLKLENERKSVL-EDIIAEANKQKELQKEEAKKL 608

  Fly  1205 TSTSEPAVLGVAKKPPEGPAKLSHPQNTTVQA-----------SHQLGISSVRPLAK------KD 1252
            ....|...|  .:|......:|.|..|....:           |.|....:::..||      ..
Yeast   609 VEAKEAKRL--KRKTVSQSQRLEHNWNKFFASFVPNLIKKNPQSKQFDHENIKQCAKDIVKILTT 671

  Fly  1253 KEKTTPTVQAPTPNRIAAGKPEPVRIGIRRSLREQLLARIKEAQAAEENSGQPTTQWP 1310
            ||....:.:|| |:.:..||...|:..| .|..::::.:.|:.:|...:|.......|
Yeast   672 KELKKDSSRAP-PDDLTKGKRHKVKEFI-NSYMDKIILKKKQKKALALSSASTRMSSP 727

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ppsNP_001247075.1 TNG2 <827..965 CDD:227367 6/13 (46%)
PHD_PHF3_like 914..963 CDD:277027 5/11 (45%)
BRK 1142..1186 CDD:197800 11/43 (26%)
TFIIS_M 1274..1396 CDD:284835 7/37 (19%)
SPOC 1623..1729 CDD:285043
SET2NP_012367.2 AWS 64..119 CDD:197795
SET_SETD2 119..260 CDD:380949
SET 215..695 CDD:225491 74/348 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4489
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.030

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