Protein Alignment pps and nsd1b

DIOPT Version :9

• Sequence 1: NP_001247075.1
• Gene: pps / 41524
• FlyBaseID: FBgn0082831
• Length: 2018
• Species: Drosophila melanogaster
• Sequence 2: XP_005173940.1
• Gene: nsd1b / 564592
• ZFINID: ZDB-GENE-080519-2
• Length: 1873
• Species: Danio rerio
• Alignment Length: 1082
• Identity: 194/1082 - (17%)
• Similarity: 345/1082 - (31%)
• Gaps: 362/1082 - (33%)

  Fly     2 SSSVFTEAPSARPAA---AEADSNLVVVYSKSGISFDERAIGNIMEEKSISTISVVRITSPTPSM 63
            ||.:.|.|..|...|   .|:.|:|......|  |||..::     |.|....|::....||.::
Zfish   462 SSRLMTRALKAMEDAEWTKESSSDLETKNCVS--SFDSPSL-----ETSDVHNSILLQKMPTAAI 519

  Fly    64 VDQEEDERLEELANFMETATDSELDSDNGSQSGGDNASEMDEHDEENHNTGDDNNSDSTETEADA 128
            .|.:||.::         :|.::|.|                   |.....||.:|..:|.|:..
Zfish   520 HDLKEDSKI---------STHAKLSS-------------------ELLCCKDDEHSVKSEDESSL 556

  Fly   129 PRTRKRVGRKPKAIKKRKRRKPKERPQIVGLRVEQFYADNTADMVVKNALKLAGVSVYKRTAETD 193
                  |.:.|.|.....|::        ...|....:..|.             |::....:.|
Zfish   557 ------VSQAPCAFHSSTRKQ--------NSHVNDLSSSPTP-------------SLHLNLKDMD 594

  Fly   194 ALMEV----IRNDHNYTPFT-SPEQLKNHKRDEKMAM--EMQAQSRK----IIMQAPGSVKLINA 247
            .:.|:    :.|:|:..|.: .|:  .|:|....:.|  :|.....|    ::::...:.:|||.
Zfish   595 NMNEISFKSLANEHSGQPLSFHPD--SNYKFSTFLMMLKDMHDSREKDGNVLVVEPLPTTELINE 657

  Fly   248 KKRVQAIPLSPVQVKVQRLPVKPHQVQQAAQLQPKVQLIRKPIHSPLPRQKPEIIANNSVNARLR 312
            :      ||....||.::          |...|.||    ||        |..:::.|.:.:.:.
Zfish   658 E------PLLISDVKDEK----------ATSKQKKV----KP--------KTNVMSENHLASTIS 694

  Fly   313 PT--RAPVKVIAPPVQEYIEDDDDAQSSD---------SAEEENADKAYDSEEMSEESDEFQE-- 364
            .|  |:..|:........|:.:.|.:|.|         |.|.|....|...::..::.|:..|
Zfish   695 KTAQRSSKKISLKKKTTDIKANIDYKSFDKLISAHRLTSKEAETNFSANVPKKRWQKFDQVSEKT 759

  Fly   365 ---------------SDNDRDSDMD----------------FDMRHSNRRN---PNKRKRVRKVV 395
                           |..:.|..||                .:....|.:|   |.:.||:||
Zfish   760 VHIVEGNCIHKTERVSSENCDVSMDGTNKSCFFGPETTSNALECNQGNCQNTEAPTECKRIRK-- 822

  Fly   396 RQTPSKPMKPLPPPPTTPQHFPELKKRKEVLEPKAPQIGQIIQMPATKSVPAVFALGRGLPSTSF 460
               |||.:      ....:.:.:|...|:..:.|...:.:|.....::.|...:         ..
Zfish   823 ---PSKRL------IEWTEEYDQLFSAKKKAKKKPDSVTKIENQKCSEPVAKTY---------DE 869

  Fly   461 LKIRP--THQSLPVKRPPLPTTPANSNVRRMPAVQLGRIVNS-PQEVKEIIINKNMASPKGV--- 519
            :|.:|  |.|.:..:.|.|.|.|.....:..|      ::|: |.:..:::..:.:..|..:
Zfish   870 VKQKPQVTEQDVSRRLPELQTPPPEDQSQSTP------LINTLPCQESQVLSAETLTPPPEIIPS 928

  Fly   520 ----FTNLNTLLGEDNNAATKSSPVPLRHRAVMSPSTPRSSYNQQMSPIVVPVPAQAHTPSKGFM 580
                .:|.:.|  :..|.......|.|..:....|:......:.:..||::|
Zfish   929 PCDNISNRDQL--QRQNPVAVGDSVCLNSKRQRKPTKKILESSIEAEPILIP------------- 978

  Fly   581 PIGVDTAQSHKLPAQIVIETHQSSSELAAENDKQLDLINSIVQDELLKSTLVEQPVVNADEDIPK 645
                    ..|:.:..:..:..|:              ||.|:.:..||    :..::.:...|.
Zfish   979 --------KRKMKSMKICSSGHST--------------NSGVEQQSSKS----KNKLSIESSDPP 1017

  Fly   646 LVKMLESTAADLDPPPVSLPTNIFPAPEMQGVGNAAAADPNNIMDTANEDEIT--ADFLQHVVGL 708
            ...||:||..::|..|..|.|.           |..:||..:.....:..::|  ::|...
Zfish  1018 SDPMLKSTEMEIDVSPAVLQTI-----------NTESADDGSDTLRCSGSQMTESSEFYSE---- 1067

  Fly   709 IEEDKQFEAEVVKQVLASTEPGTLDAIVSMPTSIEPVDVPQVQAHTNLL-----------PNAS- 761
            .||:.|.:..::.....|.|.|.       .||::....|..:...:||           |..:
Zfish  1068 REENSQSDKVLLDSRRLSEEKGG-------STSVKENVCPMCEKQGDLLLCEGQCCGAFHPQCTG 1125

  Fly   762 LTEP------AQSMTS---LPIACSTPSRSVAASTPPTSAKVVRGYGRVIYLPPIEAPTTRAKRR 817
            |.||      .|..||   ...||......|.....|...|...|.....:.|.:  |..||.|.
Zfish  1126 LNEPPTGKFLCQECTSGVHSCFACKRLGEDVRRCMVPGCGKFYHGECAASHAPTV--PLNRAFRC 1188

  Fly   818 AQF---------PSAPGMA------------ATSSSD----AGNLSFGESSLDASINQPLNTSSL 857
            ...         |:.|.:|            |..|||    ||:::..:|::..
Zfish  1189 PLHACLSCFILNPANPSVAKGQLTRCIRCPVAYHSSDFCIPAGSVTLTDSNIVC----------- 1242

  Fly   858 SNDSQPGSGPKRPNPREPSMARRSTAPRRSKKLDASQNNDPDASESQEDDDDPNKLWC-ICRQPH 921
                        ||...|....|                         :.:..|..|| :|.:..
Zfish  1243 ------------PNHFTPRKGCR-------------------------NHEHVNVSWCFVCSEGG 1270

  Fly   922 NNRFMICCDLCEDWFHGTCVGVTKAMGTDMENKGIDWKCPKC 963
            :   ::||:.|...||..|:.:....|:        |.|..|
Zfish  1271 S---LLCCESCPAAFHRECLNIDMPEGS--------WYCNDC 1301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pps	NP_001247075.1	TNG2	<827..965	CDD:227367	26/154 (17%)
		PHD_PHF3_like	914..963	CDD:277027	12/49 (24%)
		BRK	1142..1186	CDD:197800
		TFIIS_M	1274..1396	CDD:284835
		SPOC	1623..1729	CDD:285043
nsd1b	XP_005173940.1	PWWP	132..>204	CDD:321985
		TOP2c	<652..1020	CDD:330395	76/462 (16%)
		PHD_SF	1098..1140	CDD:328929	8/41 (20%)
		PHD_SF	1145..1191	CDD:328929	11/47 (23%)
		PHD_SF	1193..1245	CDD:328929	11/74 (15%)
		PHD4_NSD1	1262..1301	CDD:277126	12/49 (24%)
		WHSC1_related	1307..1401	CDD:99899
		AWS	1444..1494	CDD:197795
		SET	1497..1618	CDD:214614
		PHD5_NSD1	1668..1710	CDD:277129

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030