Protein Alignment pps and ash1

DIOPT Version :9

• Sequence 1: NP_001247075.1
• Gene: pps / 41524
• FlyBaseID: FBgn0082831
• Length: 2018
• Species: Drosophila melanogaster
• Sequence 2: NP_001246834.1
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Alignment Length: 1640
• Identity: 309/1640 - (18%)
• Similarity: 524/1640 - (31%)
• Gaps: 504/1640 - (30%)

  Fly   438 QMPATKSVPAV--FALGRGLPSTSFLK-----IRPTHQSLPVKRPPLPTTPANSNVRRMPAVQLG 495
            |...:||:.:.  |::.|.  .|..|:     ||||...:..|:||.....:..:.....:....
  Fly    35 QSSQSKSIKSATQFSVQRS--DTDGLRMRISAIRPTLGVVATKKPPKSRKMSTQDTESGCSEAKN 97

  Fly   496 RIVNSPQEVKEIIINKNMASPKGVFTNLNTLLGEDNNAATKSSPVPLRHRAVMSPSTPRS----- 555
            |.|:...:||    .|.:||..|:               :||..|....::.:|..:..|
  Fly    98 RAVSKKVKVK----RKKLASSSGI---------------SKSDKVSKSKKSQISAFSSDSEDDLP 143

  Fly   556 -SYNQQMSPIVV--PVPAQAHTPSKGFMPIGVDTAQSHKLP--AQIVIETHQSSSE--------L 607
             ..:||.:|.|:  .:...|.:.||..:.||: ::..::||  .|..|:..:|.:|        .
  Fly   144 LKVHQQRAPRVLLSAIIQAAQSASKPTLDIGI-SSSDNELPNLVQAAIKRVESDTEDTTVEGSFR 207

  Fly   608 AAENDKQLDLINSIVQDELLKSTLVEQPVVNADEDIPKLVKMLESTAADL-------DPPPVSLP 665
            .|..||.|....|.:..:.::.|.:....|||.....|:.|..|.|....       ..|...:|
  Fly   208 KAAKDKNLPQYQSTLLQDFMEKTQMLGQTVNAKLAEEKVAKAKEETLVQTAVPRKRRGRPKKVVP 272

  Fly   666 TNIFPAPEMQGVGNAAAADPNNIMDTANEDEITADFLQHVVGLIEEDKQFEAEVVKQVLASTEPG 730
            |  .|||...|.....:||...|..|:...                              ||.|.
  Fly   273 T--VPAPGNSGPAINESADSGVISTTSTTQ------------------------------STTPS 305

  Fly   731 TLDAIVSMPTSIEPVDVPQVQAHTNLLPNASLTEPAQSMTSLPIACSTPSRSVAASTPPTSAKVV 795
                             |::| :.|.:|..          |||||.|:..:...|...    |.:
  Fly   306 -----------------PKMQ-NENAVPTG----------SLPIASSSKPKIDMAYLD----KRM 338

  Fly   796 RGYGRVIYLPPIEAPTTRAKRRAQFPSAPGMAATSSSDAGNLSFGESSLDASINQPLNTSSLSND 860
            ....||:|.||      |:|||.....    .|.|||:...|.......:..:|:.....|:|..
  Fly   339 YATERVLYPPP------RSKRRQNNKK----TACSSSNKEELQLDPLWREIDVNKKFRLRSMSVG 393

  Fly   861 SQPGSGPKRPNPREPSMARRSTAPRRSKKLDASQNNDPDASESQEDDDDPNKLWCICRQPHNNRF 925
            :..|:|              ::....||.|.|......|....:..           |..||:..
  Fly   394 AASGTG--------------ASTTICSKVLAAKSGYVSDYGSVRHQ-----------RSSHNHNS 433

  Fly   926 MICCDL-CEDWFHGTCVGVTKA-MGTDMENKGIDWK--CPKCVKRQEERSQPRITDMLV--TRPT 984
            ....|. |:..:.      ||: |......|...::  |.:..|......:.|...||:  :...
  Fly   434 GYKSDASCKSRYS------TKSCMSRRSRAKSCGYRSDCKESGKSGLRMRRKRRASMLLKSSADD 492

  Fly   985 TQPEQRPSETKVLTTTAEIVQVAAPSAPRRTLPVVLTVASSPMRIPMAKPA-KKFPTGAISHQQQ 1048
            |..:|            :|:|:|..|         |..:|......::||: |..||.:.|.:..
  Fly   493 TVEDQ------------DILQLAGLS---------LGQSSEESNEYISKPSLKSLPTTSASKKYG 536

  Fly  1049 QQLNFIRLG-----------PSPGKRISETLCVVCKRPASTSSVYCGEECIRKYAQSAIQAHAAT 1102
            :...::..|           .:|...||:.:....:.||.:.| .|..:..|..|.|...::.:.
  Fly   537 EINRYVTTGQYFGRGGSLSATNPDNFISKMMNQRKETPAPSKS-SCKIKSRRSSAASMCSSYVSG 600

  Fly  1103 KGPLPQNAGAQSLLNN---SFDAK-------------------------KNKKKDLFEDVLR--- 1136
            ...:.:....:|..:|   :.|:|                         .:.|:.|..|..:
  Fly   601 VSRMRRRHRRKSFSHNKSLNIDSKLLTEIEIITSTFNSRCRIQDDRLTGSSGKEKLLADANKLQA 665

  Fly  1137 -----------------QADTVSKVERINVFERKSGRVITGHMAPSAHQFRKWLQENPSFEVLPS 1184
                             .|.|:||..:..:.:||....:......||           |....|:
  Fly   666 TLAAPSPAQQLTLNGGGPASTLSKPLKRGLKKRKLSEPLVDFAMLSA-----------SASGTPN 719

  Fly  1185 GTVQSADAEKRLLKGAPEAATSTSEPAVLGVAK---------KPPEGPAKLSHPQNTTVQASHQL 1240
            |:..|....||..|.:....:|:.:...|.:.|         :||...|..:...|....|:...
  Fly   720 GSGSSNGNTKRRHKKSQSNDSSSPDDHKLPLKKRHYLLTPGERPPAEVAFANGKLNAEAWAAAAA 784

  Fly  1241 GISSVRPL-------AKKDKEKTTP----TVQAPTP-------------------NRIAAGKPEP 1275
            ...|....       |:..|...||    .::.||.                   |.|:.||...
  Fly   785 AAKSTASTKSQAQFNARSVKSALTPKKRHLLEQPTSVSGAGSSASNSPLRIVVDNNSISGGKLLD 849

  Fly  1276 VRIGIRRSLREQLL--ARIKEAQAAEE--NSGQPTTQWPTVLEVDQFVKNVELEM---FNSFGRD 1333
            :......||::|..  |..::..||::  ....|...:|   ....|..:||||:   .:.....
  Fly   850 ISPSSLCSLKQQRRGGAAKQKVSAAKDLVQLQSPAGSYP---PPGVFEPSVELEIQIPLSKLNES 911

  Fly  1334 VGAKYKAKYRSLMFNIKDRKNRTLFEKICAKQVEPRQLVRMTPEQLASQELAKWREEENRHQLDM 1398
            |..  ||:..|.:.:..|.|..|      .|:|..|.:..:..:...:..|.:.|::.||.....
  Fly   912 VIT--KAEVESPLLSALDIKEDT------KKEVGQRVVETLLHKTGGNLLLKRKRKKINRTGFPT 968

  Fly  1399 IKKSELDLLACAQNYVVKTHKGEEVIATKVDVTLPEENVSE--ASSMADTKQTSLVSEPSTSTLE 1461
            :::.:..:..            |:.....:|...||.:..:  ..|:.:|:.::.|:..:.....
  Fly   969 VRRKKRKVSV------------EQQTTAVIDEHEPEFDPDDEPLQSLRETRSSNNVNVQAAPNPP 1021

  Fly  1462 RSTSR-EKAGSSKE-----KRHKSHK-------HHHRKRSRSRSNSRGRSVDKRHRRQHNEGGEQ 1513
            ....| .:||.::|     ...|:.:       ...|.::.:|...|||.  .::|.|.....:.
  Fly  1022 LDCERVPQAGEARETFVARTNQKAPRLSVVALERLQRPQTPARGRPRGRK--PKNREQAEAAPQP 1084

  Fly  1514 PGSGEREHRSREKQSRE-----RDEIVPSPLP-----------------------------KKRD 1544
            |...|.|.|..:|:.|:     .:|..|:|.|                             |:|.
  Fly  1085 PPKSEPEIRPAKKRGRQPKQPVLEEPPPTPPPQQKKNKMEPNIRLPDGIDPNTNFSCKIRLKRRK 1149

  Fly  1545 ENDQSPVPKKTAEKKTE-ASAYNLVDQILESEKTVE---QAANLGKPKPSPKPLPTLPSSLKAPE 1605
            ..:....|||  ||..: .:...:..:|..|::.::   :|..|........|||.  |....|.
  Fly  1150 NLEAGTQPKK--EKPVQPVTVEEIPPEIPVSQEEIDAEAEAKRLDSIPTEHDPLPA--SESHNPG 1210

  Fly  1606 PMDNYSRYLHGLTTSSLWSGTLKMIDLADFEIVMYPVQG--NCHQLGNLMPSQMDVIGRITRVNV 1668
            |.|    |.....:|...:.|..:..|:..: ..|.|.|  :.|...:|||..
  Fly  1211 PQD----YASCSESSEDKASTTSLRKLSKVK-KTYLVAGLFSNHYKQSLMPPP------------ 1258

  Fly  1669 WEYIKKLKKSP--TKEVVIVNIFPASP-SETY----------KFDLFFEYLDSRQRLGVLGVDSD 1720
                .|:.|.|  .::|...::.|..| .|.|          .:|:::.|.:|
  Fly  1259 ----AKVNKKPGLEEQVGPASLLPPPPYCEKYLRRTEMDFELPYDIWWAYTNS------------ 1307

  Fly  1721 QIRDFYIFPLGSGDKLPPALQTAEPVP----------FYEEAQRPNTLLGI-------------- 1761
                          |||    |...||          .|.|:.||| |.|.
  Fly  1308 --------------KLP----TRNVVPSWNYRKIRTNVYAESVRPN-LAGFDHPTCNCKNQGEKS 1353

  Fly  1762 -IVRCLSKRPADAVPSTPSVPTPVPALSSKVAKRSRSSISYPAQSSPKRKISTHSTSSKDDEF-- 1823
             :..||::     :..|...|:..||                .:....:||..|:.:...:.|
  Fly  1354 CLDNCLNR-----MVYTECSPSNCPA----------------GEKCRNQKIQRHAVAPGVERFMT 1397

  Fly  1824 ---DIDAIIKAPIAK 1835
               ......|.||||
  Fly  1398 ADKGWGVRTKLPIAK 1412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pps	NP_001247075.1	TNG2	<827..965	CDD:227367	25/141 (18%)
		PHD_PHF3_like	914..963	CDD:277027	10/52 (19%)
		BRK	1142..1186	CDD:197800	8/43 (19%)
		TFIIS_M	1274..1396	CDD:284835	27/128 (21%)
		SPOC	1623..1729	CDD:285043	20/120 (17%)
ash1	NP_001246834.1	AWS	1340..1388	CDD:197795	9/68 (13%)
		SET	1392..1512	CDD:214614	6/21 (29%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.030