Protein Alignment pps and si:ch73-181d5.4

DIOPT Version :9

• Sequence 1: NP_001247075.1
• Gene: pps / 41524
• FlyBaseID: FBgn0082831
• Length: 2018
• Species: Drosophila melanogaster
• Sequence 2: XP_003201203.2
• Gene: si:ch73-181d5.4 / 100538306
• ZFINID: ZDB-GENE-100922-118
• Length: 2142
• Species: Danio rerio
• Alignment Length: 1479
• Identity: 317/1479 - (21%)
• Similarity: 502/1479 - (33%)
• Gaps: 440/1479 - (29%)

  Fly   781 RSVAASTPPTSAK-VVRGYGRVIYLPPIEAPTTRAKRRAQFPSAPGMAATSSSDAGNLSFGE--- 841
            |:..|....|:|| ..||.|||.    :.|..:.::|     :..|..:..:.|:.:|:..|
Zfish    66 RAADAGMGLTAAKRGRRGRGRVW----VHADESSSER-----NTGGATSDRAEDSDDLNLQEMRR 121

  Fly   842 --------SSLDASINQPLNTS---SLSNDSQPGS-GPKRP--NPREPSMARRSTAPRRSKKLDA 892
                    .|.|...|..|...   ..|:|::..: |.|:.  ..||.:.........|:::|
Zfish   122 RALARRMRESTDGERNDGLGEQEGVEQSDDTESAAEGEKQGLFTDREAADTLSFAGDERNERL-- 184

  Fly   893 SQNNDPDASESQE--------DDDDPNKLWCICRQ-PHNNRFMICCDLCEDWFHGTCVGVTKAMG 948
             ||:    ||.||        ::|:.:.:...|.| ..:||..|.|..|..:.|..|||:.:..
Zfish   185 -QNH----SEHQEEICISDKHEEDNQDAVCGTCGQRDDSNRLTISCKSCGAFRHVDCVGIFETW- 243

  Fly   949 TDMENKGIDWKCPKCVKRQEERSQPRITDMLVTRPTTQPEQRPSETKVLTTTAEIVQVAAPSAPR 1013
                 |..::.||.|.:.:|...:.:.||
Zfish   244 -----KNEEYMCPPCTENRELTCRNQKTD------------------------------------ 267

  Fly  1014 RTLPVVLTVASSPMRIPMAKPAKKFPTGAISHQQQQQL-----NFIRLGP---SPGKRISETLCV 1070
                               .|..|....:|:....||:     |.:.:.|   .||
Zfish   268 -------------------DPCLKQEISSINMVDVQQMIKVEQNVVEVSPKCIGPG--------- 304

  Fly  1071 VCKRPASTSSVYCGEECIRKYAQSAIQAHAATKGPLPQNAGA---------QSLLNNSFDAKKNK 1126
             |...|...|||||..||.::|..||:   ....|.|:...|         :|.|...|..|.||
Zfish   305 -CSSDALPESVYCGHRCIVQHAAVAIK---TLSEPKPEVKSAVVPSLKSEKRSFLAKLFKVKVNK 365

  Fly  1127 KKDLFEDVLRQADTVSKVERINVFERKSGRVITGHMAPSAHQFRKWLQENPSFEVLPSGTVQSAD 1191
            ..       .:.:...|.|     |:....|.:..:|..|........|:....|..|..|..|.
Zfish   366 SP-------AEREQEGKAE-----EKSEESVCSSAVADPAQTTTATPPEHHKLPVKDSSDVDPAP 418

  Fly  1192 -AEKRLLKGAPEAATSTSEPAVLGVAKKPPEGPAKLSHPQNTTVQASHQLGISSVRPLA--KK-- 1251
             ..|....|.|:.|.|:.:.....:.||.....||.:.|.:..::...  |..|..|||  ||
Zfish   419 LCMKSPPSGLPQDAPSSEKAPAAPLLKKSTPARAKKTMPGSPRLELLK--GALSKSPLASLKKSS 481

  Fly  1252 DKEKTT------PTVQAPTPN------RIAAGKPE-PVRI------------------------- 1278
            |..:||      |.|.|..|.      .:::|.|| |||:
Zfish   482 DSSRTTEVSIRAPVVSARAPEVSSKAPEVSSGPPEVPVRVPEISSRAPEVPASFLEVSSKAPEVS 546

  Fly  1279 ----------------GIRRSLR---------EQLLARIKEAQAAEE-------NSGQP--TTQW 1309
                            .::.|:|         |..::.:|.:..|.|       :||.|  :::.
Zfish   547 VRAPEISSRAPEVPVSALKVSVRAPEISSRAPEVPVSALKVSVRASEISSRAPASSGVPEVSSRS 611

  Fly  1310 PTVL--------------------------------------EVDQFVKNVELEMFNSFGRDVGA 1336
            |.|.                                      ||::|..::|.||| |.......
Zfish   612 PEVSVLDPRCSPLLIRQNIRCLLTKVLLERLNQSDGLIFSENEVEKFAVDLEKEMF-SMCYTTDQ 675

  Fly  1337 KYKAKYRSLMFNIKDRKNRTLFEKICAKQVEPRQLVRMTPEQLASQELAKWREEENRHQLDMIKK 1401
            :|::|.:.|...:||.:|:.|..::....:...:|:     .::.|::.|....:...|:.|  |
Zfish   676 EYRSKCQDLSLRLKDPQNKELCLQVLKGNLPVSRLI-----SVSQQDIVKETSADPEPQISM--K 733

  Fly  1402 SELDLLACAQNYVVKTHKGEEVIATK--VDVTLPEENVSEASSMADTKQTSLVSEP--STSTLER 1462
            .|...|:........:.......|.|  ::...|.|..|.||.:..|::..:.|:.  ..|::.:
Zfish   734 EESSFLSVDMEEATPSPPAAAAAAEKESMNTDTPTEEKSSASPLKQTEEREISSDSPHGMSSMLK 798

  Fly  1463 STSREKAGSSKEKRHKSHKHHHRKR-SRSRSNSRGRSVDKRHRRQHNEGGE------QPGSGERE 1520
            .|:.|         ||.|....:.| ...:|::.|....|...:.....||      ||.....:
Zfish   799 DTTAE---------HKLHVFDLKCRICTGQSSTDGNCDIKPKTKTETVEGESSERVVQPTDAALD 854

  Fly  1521 HRSREKQSRERDEIVPSPLPKKRDENDQSPV--------------PKKTAEKKTEASAYNLVDQI 1571
            ....|..:....|.|.|    |....|.|||              |:.....||.:|..  .:.:
Zfish   855 CSDLESPASPSAEDVES----KTHTVDYSPVVIPAVPLVSISGRDPRTAQYHKTASSPG--TESV 913

  Fly  1572 LESEKTVEQAANLGKPKPSPKPLPT---LPSS-LKAPEPMDNYSRYLHG--------------LT 1618
            ..|.:|...|.|..:.....:|.|.   ||.| |..|.|...::.|...              ..
Zfish   914 STSLQTPNPARNTTEAVNETQPTPVSVRLPKSILMKPSPSSLHTSYASNTRLADCDKGTRQFLAK 978

  Fly  1619 TSSLWSGTLKMIDLADFEIVMYPVQGNCHQLGNLMPSQMDVIGRITRVNVWEYIKKLKKSPTKEV 1683
            .|.||.|.|.|..:|.|....|.:.|:...|...:|..:.:.|||....||||:..:|.|..||:
Zfish   979 QSILWKGFLNMPTVAKFVTKGYLISGSPDILKEELPDTIHIGGRILPQTVWEYVDLIKTSEAKEL 1043

  Fly  1684 VIVNIFPASPSETYKFDLFFEYLDSRQRLGVLGVDSDQIRDFYIFPLGSGDKLPPALQTAEPVPF 1748
            .::...|||..|...:...|.|.:||:|.||:......|:|.|:.||.:...:|.||...|. |.
Zfish  1044 SLIRFHPASDEEEVAYVSLFSYFNSRRRFGVVSNICKHIKDLYLIPLCTKQSIPAALLPIEG-PG 1107

  Fly  1749 YEEAQRPNTLLGIIVRCLSKRPADAVP----------------STPSV-----PTPVPALSSKVA 1792
            .|: ..||.|:|:.| |...:..|..|                |||:.     |.|..|..:.|.
Zfish  1108 LEQ-DHPNLLIGLAV-CQKLKHPDRPPQDAAEKKSKSLIYKESSTPTSINDLGPYPTKACDADVF 1170

  Fly  1793 KRSRSSISYPAQSSP--KRKISTHSTSSKDDEFDIDAII------KAPIAKL----------QKT 1839
            ..|.||.|..:.|.|  |..:|.:..:|||....:..|:      |.|::.|          |:.
Zfish  1171 LNSHSSGSPSSSSVPVSKPSMSVNMGTSKDSTTPLQTILNTLFGQKKPLSDLNECKKVDDVQQED 1235

  Fly  1840 APKVVPQPSVPNDADEPYSPGGSDDELVPSAPQRPNDLERQVNEINKQIAAQQMEIAGLLKVEPT 1904
            |.|.|  ..:|.| .|.|.|..|::.:|..:|.:|.:                      ||:.|
Zfish  1236 AGKCV--DDMPYD-PEDYDPAVSNEAMVSLSPPKPVE----------------------LKIPP- 1274

  Fly  1905 GSASSSNVLAAISIPANLSKILASIKDKTNLPSSADDGDEEYNPEDD---ITATSSFASKKPRSK 1966
                                          |..:.:|.|..|:||::   |....:..|..|:
Zfish  1275 ------------------------------LAINNEDDDRPYDPEEEYCTIDHGETLRSNLPK-- 1307

  Fly  1967 GRLAHLSEAELLSMVPDNLAGVI--PRSSRTRHQLAQSPLTPTPLPPPP 2013
                 :|||:.:...|.....:.  |.......:: |:.||...:|..|
Zfish  1308 -----VSEAKSVEKPPTANTDIAYDPEDESVFEEM-QNYLTNNAIPHKP 1350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pps	NP_001247075.1	TNG2	<827..965	CDD:227367	37/163 (23%)
		PHD_PHF3_like	914..963	CDD:277027	14/49 (29%)
		BRK	1142..1186	CDD:197800	9/43 (21%)
		TFIIS_M	1274..1396	CDD:284835	33/219 (15%)
		SPOC	1623..1729	CDD:285043	35/105 (33%)
si:ch73-181d5.4	XP_003201203.2	PHD_SHPRH	211..253	CDD:277022	14/47 (30%)
		TFIIS_M	626..717	CDD:284835	16/96 (17%)
		PHA03255	820..>963	CDD:165513	33/148 (22%)
		SPOC	983..1089	CDD:285043	35/105 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I7009
eggNOG	1	0.900	-	-		E1_KOG1634
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25216
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.900