DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5196 and zdhhc8b

DIOPT Version :9

Sequence 1:	NP_650191.1	Gene:	CG5196 / 41522	FlyBaseID:	FBgn0038039	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_840089.2	Gene:	zdhhc8b / 352941	ZFINID:	ZDB-GENE-030407-3	Length:	751	Species:	Danio rerio

Alignment Length:	327	Identity:	78/327 - (23%)
Similarity:	128/327 - (39%)	Gaps:	91/327 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LFLLLSTLATFNYVMATLTGPGLMPKQWHPKDPKDAQF----------------LQYCKKCEGYK 100
            ||:|.      |:.|||...||:.|:....:| ||..|                :::|..|..|:
Zfish    56 LFVLA------NFSMATFMDPGVFPRADEDED-KDDDFRAPLYKNVEIKGIQVRMKWCATCHFYR 113

  Fly   101 APRSHHCRKCDRCVKKMDHHCPWINHCVGWANHAYFTYFLLFSILGSLQGTVVLCCSFWRGIYRY 165
            .||..||..||.||::.||||||:|:|:|..|:.||..|||     ||...:|       |::.:
Zfish   114 PPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLL-----SLSVHMV-------GVFSF 166

  Fly   166 --YYLTHGLAHLASVQFTLLSIIMCILG------MGLAIGVVIGLSMLLFIQLKTIVNNQTG--- 219
              .::.|.|..|:::..|:..::||:.|      |||.     |..|:|..:.:|.....||
Zfish   167 GLLFMLHHLETLSALHTTVTLVVMCVTGLFFIPVMGLT-----GFHMVLVARGRTTNEQVTGKFR 226

  Fly   220 ---------------------------------IEIWI----VEKAIYRRYRNADCDDEFLYPYD 247
                                             |.:.:    :...:..|:.:....|..::...
Zfish   227 GGVNPFTRGCGGNVKHVLCSPLAPRYIADPRKKIPVTVTPPFLRPDLSNRHISVKVSDNGIHSNI 291

  Fly   248 LGWRANLRLVFNDECQKRGDGIEWPVVEGCDQYTLTREQLAQKEEKRARTRTFKCTRPVTGRWLP 312
            |  |:..:...|....|..|. :.|:....|:|...:.||...||....::....:.|...::.|
Zfish   292 L--RSKSKTSLNGMDDKSIDA-QPPLPPKADRYNQIKSQLTSSEESSLSSKPTNPSTPAMFKYRP 353

  Fly   313 IF 314
            .|
Zfish   354 SF 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5196	NP_650191.1	zf-DHHC	89..223	CDD:279823	48/193 (25%)
zdhhc8b	NP_840089.2	zf-DHHC	99..224	CDD:279823	45/141 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..346		11/53 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	437..461
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	633..659
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	666..685
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	703..736
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810