DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5196 and Zdhhc23

DIOPT Version :9

Sequence 1:	NP_650191.1	Gene:	CG5196 / 41522	FlyBaseID:	FBgn0038039	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001007461.1	Gene:	Zdhhc23 / 332175	MGIID:	2685625	Length:	425	Species:	Mus musculus

Alignment Length:	312	Identity:	69/312 - (22%)
Similarity:	107/312 - (34%)	Gaps:	132/312 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLH---WGPITALSIIKCITLTTLYMNSMWWPPNKSFAGFAH----QALFLLLSTLATFNYV--- 65
            |||   |.     .::..:.||:|.|.::|      :....|    |.||.|...|.:..|:
Mouse    96 FLHVASWH-----FLLGVVVLTSLPMLALW------YYYLTHRRKEQTLFFLSLGLFSLGYMYYV 149

  Fly    66 ---------------MATLT---------------GPGLMPKQWHPKDPKDAQF----------- 89
                           :|.||               .||.:.   :.|.|.::|.
Mouse   150 FLREVVPQGRVGPTQLALLTCGLLLILLALYRAKKNPGYLS---NDKSPSNSQIECPVKKGQEKT 211

  Fly    90 ------------------------------------LQYCKKCEGYKAPRSHHCRKCDRCVKKMD 118
                                                ..:|.||:..:..|:.|||.|..||::||
Mouse   212 KGFPGTDASGSLNNRTLKDDVRGSSRVGLDSPAKVKEDWCAKCQLVRPARAWHCRICGICVRRMD 276

  Fly   119 HHCPWINHCVGWANHAYF----TYFLLFSILGSLQGTVVLCCS---------FWRGIYRYYYLTH 170
            |||.|||.|||.:||..|    :.|||.|:.| :..|:...|.         :..|:|..|
Mouse   277 HHCVWINSCVGESNHQAFILALSIFLLTSVYG-ISLTLNTICRDRSLFTALFYCPGVYANY---- 336

  Fly   171 GLAHLASVQFTLLSIIMCILGMGLAIGVVIGLSMLLFIQLKTIVNNQTGIEI 222
                .:::.||      |:   ..::.:..|::.:..|||..|..|.|..|:
Mouse   337 ----SSALSFT------CV---WYSVIITAGMAYIFLIQLINISYNVTEREV 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5196	NP_650191.1	zf-DHHC	89..223	CDD:279823	45/194 (23%)
Zdhhc23	NP_001007461.1	DHHC	248..374	CDD:396215	44/143 (31%)
Zdhhc23	NP_001007461.1	Interaction with NOS1. /evidence=ECO:0000250	422..425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810