DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sccpdh2 and Sccpdh

DIOPT Version :9

Sequence 1:	NP_650190.1	Gene:	Sccpdh2 / 41521	FlyBaseID:	FBgn0038038	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001014007.1	Gene:	Sccpdh / 305021	RGDID:	1311440	Length:	429	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	170/434 - (39%)
Similarity:	257/434 - (59%)	Gaps:	30/434 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IIFGASGFTGKYTVFE------AVSVLKGLQWGIAGRNQEKLQSVLREMGAK--SKTDLSQTPIV 65
            ::||||||||::...|      |......|.|.:|||::||||.||.:...|  ..|..|:..|:
  Rat    11 VVFGASGFTGQFVTEEVAREQMASEQSSRLPWAVAGRSKEKLQQVLEKAAQKLGRATLSSEVGII 75

  Fly    66 IADVNNEASLLEMAKRCRILVNTAGPYRFFGERVVRACIEAGTHHVDVSGEPQYMETMQLRYHDL 130
            |.|::|.|||.||||:..:::|..|||||:||.||:||||.||..:|:.||||::|.|.::||:.
  Rat    76 ICDISNPASLDEMAKKATLVLNCVGPYRFYGEPVVKACIENGTSCIDICGEPQFLELMHVKYHEK 140

  Fly   131 AKERGVYVISACGFDSIPADMGVTFVEKNFDGVVNSVENFVHLGVKGGTKGTGSAALNTGTWESA 195
            |.|:|||:|.:.||||||||:||.:.....:|.:.:||:|  |.:..|.:|   ..::.|||:||
  Rat   141 AAEKGVYIIGSSGFDSIPADLGVLYTRNQMNGTLTAVESF--LTINSGPEG---LCIHDGTWKSA 200

  Fly   196 IHAIANRSESVAIRRKLFPERLPNFHPALKSRSPLSRAAEVDNKVILPFPETDRSVVMRSQRFLY 260
            |:...::.....:|.....:.:|.....||.|.|:|...|: |...:||..:|.|||.|:||:|:
  Rat   201 IYGFGDKGSLRKLRSVSNLKPVPVIGSKLKRRWPVSYCREL-NSYAIPFLGSDMSVVKRTQRYLH 264

  Fly   261 ELEKKRPVQMQAYMTYPSWFAASVVVLFASIIGI-MAKFSFGRQLLLKYPTVFSGGMASREGPSE 324
            |..:..|||..||:|. ....:.:.::||.:..: ..|||.|||||:|:|.:||.|..|:.||::
  Rat   265 ENLEDSPVQYAAYITV-GGITSVIKLMFAGLFFLFFVKFSIGRQLLVKFPWLFSFGYFSKRGPTQ 328

  Fly   325 ARMERSFFRMTMKATGWP---KSEKLAETTDQYTSPPTKTLTVRVTGPNPGYGSTCVALLSTAKT 386
            .:|:.|.|.||....|:.   .:||         :.|...:..:|.||..||.:|.:|::..|.|
  Rat   329 KQMDESSFTMTFFGQGYSHGVSAEK---------NKPNIRICTQVKGPEAGYVATPIAMVQAAVT 384

  Fly   387 ILNESDKMPGSGGVLPPGAAFRGTSLISELEKHEHGIKFEIVAN 430
            .||::..:|..|||..|||||..|.||..|  ::|||:|.::::
  Rat   385 FLNDASDLPKGGGVFTPGAAFSRTKLIDRL--NQHGIQFSVISS 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sccpdh2	NP_650190.1	COG3268	7..416	CDD:225807	165/418 (39%)
Sccpdh2	NP_650190.1	Sacchrp_dh_NADP	9..139	CDD:281434	65/137 (47%)
Sccpdh	NP_001014007.1	COG3268	1..421	CDD:225807	169/427 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349173
Domainoid	1	1.000	172	1.000	Domainoid score	I3627
eggNOG	1	0.900	-	-		E1_COG3268
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9334
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2643
OMA	1	1.010	-	-		QHG56565
OrthoDB	1	1.010	-	-		D302978at33208
OrthoFinder	1	1.000	-	-		FOG0002586
OrthoInspector	1	1.000	-	-		otm45637
orthoMCL	1	0.900	-	-		OOG6_101495
Panther	1	1.100	-	-	O	PTHR12286
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1697
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770