DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9f2 and CYP709B1

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_566092.1	Gene:	CYP709B1 / 819310	AraportID:	AT2G46960	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	525	Identity:	129/525 - (24%)
Similarity:	238/525 - (45%)	Gaps:	89/525 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KDRGIAYEKPVLYFGNMAGMFLRKRA------------MFDIVCDLYTKGGSK--KFFGIFEQRQ 78
            |::||:.....:::||::.:...||.            :|..:...|.|..|:  :.|..:...:
plant    39 KNQGISGPNYRIFYGNLSEIKKMKRESHLSILDPSSNDIFPRILPHYQKWMSQYGETFLYWNGTE 103

  Fly    79 PLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARWKDMRSTLSP 143
            |.:.:.||:|.|.:        ::::..|...|...|..:..:....|..:..|.|...|..|:|
plant   104 PRICISDPELAKTM--------LSNKLGFFVKSKARPEAVKLVGSKGLVFIEGADWVRHRRILNP 160

  Fly   144 AFTGSKMRQMFQLMNQVAKEAVDC-LK-----QDDSRVQENE-----LDMKDYCTRFTNDVIAST 197
            ||:..:::.|..:|       ||| ||     :.:|..:|.|     .:|.:...|.|.|:||::
plant   161 AFSIDRLKIMTTVM-------VDCTLKMLEEWRKESTKEETEHPKIKKEMNEEFQRLTADIIATS 218

  Fly   198 AFGLQVNSFKDRENTF-YQMGKKLTTFTFLQSMKFMLFFALKGLNKI-----LKVELFDRKSTQY 256
            |||   :|:.:....| .||..|....|.|..:      ::.|...:     ::|...:||....
plant   219 AFG---SSYVEGIEVFRSQMELKRCYTTSLNQV------SIPGTQYLPTPSNIRVWKLERKMDNS 274

  Fly   257 FVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFET 321
            ..|::...::.:.::.   .|::.:|::|   ..||..:    |:.|..:|:.:|..|||.|.||
plant   275 IKRIISSRLQSKSDYG---DDLLGILLKA---YNTEGKE----RKMSIEEIIHECRTFFFGGHET 329

  Fly   322 SAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELT--YEAIMGMKYLDQVVNEVLRKWPAA 384
            ::.|:.:|...|..:||.|::|.||:.:..    |||.|  .|....:|.::.|:.|.||.:...
plant   330 TSNLLAWTTMLLSLHQDWQEKLREEIFKEC----GKEKTPDSETFSKLKLMNMVIMESLRLYGPV 390

  Fly   385 IAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYF-ENPMKFDPERFSD-ENKESIQP 447
            .|:.||.:.:|...    .:|:.||..:.:|....|.|...: .:..||:|.||:: .::.:..|
plant   391 SALAREASVNIKLG----DLEIPKGTTVVIPLLKMHSDKTLWGSDADKFNPMRFANGVSRAANHP 451

  Fly   448 FTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSC-----IPLELITSGFQLSPKGG 507
            .....|.:|.|.|||..|.::|||.|:..:|:.:||.   ..|     .|::.:|    :.|:.|
plant   452 NALLAFSVGPRACIGQNFVMIEAKTVLTMILQRFRFI---SLCDEYKHTPVDNVT----IQPQYG 509

  Fly   508 FWIKL 512
            ..:.|
plant   510 LPVML 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	125/513 (24%)
CYP709B1	NP_566092.1	p450	32..517	CDD:299894	129/525 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810