DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9f2 and tbxas1

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_991172.2	Gene:	tbxas1 / 792041	ZFINID:	ZDB-GENE-030131-8805	Length:	546	Species:	Danio rerio

Alignment Length:	545	Identity:	167/545 - (30%)
Similarity:	268/545 - (49%)	Gaps:	66/545 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFAIAAALFYRWASANNDFFKDR-GIAYEKPVLYFGNMAGMFLRKRAMFDIVCDLYTKGGSKKFF 71
            ||.::.:|.| |.|.:.....:| ||.:.||:.:.||:. ||  :...|....||..|.|  :..
Zfish    24 LFLLSLSLLY-WYSISPFSNLERCGIKHPKPLPFIGNLM-MF--RNGFFKSQADLINKYG--RIC 82

  Fly    72 GIFEQRQPLLMVRDPDLIKQITIKDFDHFINH---RNVFATSSDDDPHDMSNLFGSSLFSMRDAR 133
            |.:..|:..:::.|||:::|:.:|:|:.|.|.   |.:....||            ||..::..:
Zfish    83 GYYIGRRSTVIIADPDMLRQVMVKEFNKFPNRMTARGITKPMSD------------SLIMLKGEQ 135

  Fly   134 WKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIASTA 198
            ||.:||.|:|.|:.:||::|..|:|...:..:..||....  .||..::......||.|||||.|
Zfish   136 WKRVRSILTPTFSAAKMKEMVPLINTATETLLRNLKSHAE--SENSFNIHKCFGCFTMDVIASVA 198

  Fly   199 FGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFF--------ALKGL--------------- 240
            ||.||:|..:.::.|.....|...|:|.:.:  |:||        .|.||
Zfish   199 FGTQVDSQNNPDDPFVHQASKFFAFSFFRPI--MIFFMAFPFLLRLLAGLLPNKSRDEMNSFFTQ 261

  Fly   241 --NKILKV--ELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEA-----RGIIQTEKTKA 296
              .|::|.  :|...:..:.|::|:||....::..::...|::|...|.     ......|.||.
Zfish   262 CIQKMIKQRDDLSPEQRRKDFLQLMLDVRTNKKFLSVEHFDVVNDADEEAYDGHENSPANESTKR 326

  Fly   297 S-AVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELT 360
            | ..|..::.:||.|.|:|..||:|||:..:.||.:.|..:.:.|::|.|||.:.....|  .:.
Zfish   327 SQQKRMMTEDEIVGQSFIFLVAGYETSSNTLAFTCYLLAVHPECQKKLQEEVDEFFSRHE--TVD 389

  Fly   361 YEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKY 425
            |..:..:||||.|:.|.||.:|.|..|.|:..:|..  ::||  .:.||..:.:||...|.||::
Zfish   390 YANVQELKYLDMVICESLRLYPPAFRVARDVEEDTV--LNGQ--FLPKGASLEIPTGFLHYDPEH 450

  Fly   426 FENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSC 490
            :..|.||.||||:.|.|....||.|.|||.|.|:|:|.|.|.||.|..:.::.:.:.....:.:.
Zfish   451 WTEPTKFIPERFTPEAKARRHPFVYLPFGAGPRSCVGMRLAQLEIKVALVHIFRRFNVLACEDTE 515

  Fly   491 IPLELITSGFQLSPKGGFWIKLVQR 515
            ||||| .|...|.||.|..:|:.:|
Zfish   516 IPLEL-KSHTTLGPKNGVMVKITER 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	156/509 (31%)
tbxas1	NP_991172.2	p450	51..536	CDD:278495	156/512 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8421
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.750