Protein Alignment Cyp9f2 and TBXAS1

DIOPT Version :9

• Sequence 1: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001159725.2
• Gene: TBXAS1 / 6916
• HGNCID: 11609
• Length: 579
• Species: Homo sapiens
• Alignment Length: 592
• Identity: 151/592 - (25%)
• Similarity: 263/592 - (44%)
• Gaps: 119/592 - (20%)

  Fly    10 AIAAALFYRWASANN-DFFKDRGIAYEKPVLYFGNMAGMFLRK---------RAMFDIVCDLYTK 64
            ::|.....:|.|.:. ...:..|:.:.||..:.||:.  |.|:         |.::..:|
Human    21 SVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLT--FFRQGFWESQMELRKLYGPLC----- 78

  Fly    65 GGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSM 129
                   |.:..|:..:::.:||:|||:.:::|.:|.|.   .|:..     :..::..|.|| :
Human    79 -------GYYLGRRMFIVISEPDMIKQVLVENFSNFTNR---MASGL-----EFKSVADSVLF-L 127

  Fly   130 RDARWKDMRSTLSPAFTGSKMRQMFQLMNQ----------------------------------- 159
            ||.||:::|..|..||:..|:.::..|:.|
Human   128 RDKRWEEVRGALMSAFSPEKLNELGLLIMQERIKGHMGGQQAPQRIPPTRLSKPSGIYVNLHYAT 192

  Fly   160 -------VAKEAVDCLKQDDSRVQE--NELDM-KDYCTRFTNDVIASTAFGLQVNSFKDRENTFY 214
                   :..:|.|.|.....|..|  :..|: :.|| .:|.||:||.|||..|:|::..|:.|.
Human   193 LPFCMVPLISQACDLLLAHLKRYAESGDAFDIQRCYC-NYTTDVVASVAFGTPVDSWQAPEDPFV 256

  Fly   215 QMGKKLTTFTFLQSMKFMLFF------------------ALKG-LNKILK--VELFDRKSTQY-- 256
            :..|:...|...:.:..:|..                  .|.| .||:::  :.|.|:::.:.
Human   257 KHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERR 321

  Fly   257 --FVRLVLDAMKYRQEHNIVRPDMINMLMEARGI---IQTEKTKASAVREWSDRDIVAQCFVFFF 316
              |:::||||........:...|::..:..:.|.   ...:...:...|..:..:||.|.|:|..
Human   322 RDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLI 386

  Fly   317 AGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIM---GMKYLDQVVNEVL 378
            ||:|.....:.|..:.|..|.|.|::|..||....:    |.:..|...   |:.|||.|:.|.|
Human   387 AGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKE----KHMAPEFCSLEEGLPYLDMVIAETL 447

  Fly   379 RKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKE 443
            |.:|.|....||..:|.  :|.||::..  |.|:.:.....|.||:::.:|..|:||||:.|.::
Human   448 RMYPPAFRFTREAAQDC--EVLGQRIPA--GAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ 508

  Fly   444 SIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGF 508
            ..:||||.|||.|.|:|:|.|..|||.|..:.::|..:||....::.:||:| .|...|.||.|.
Human   509 QHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL-ESKSALGPKNGV 572

  Fly   509 WIKLVQR 515
            :||:|.|
Human   573 YIKIVSR 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	143/558 (26%)
TBXAS1	NP_001159725.2	p450	47..576	CDD:306555	144/561 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I2940
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8623
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2429
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.900