DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9f2 and cyp3c2

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_021330384.1	Gene:	cyp3c2 / 558473	ZFINID:	ZDB-GENE-081103-62	Length:	503	Species:	Danio rerio

Alignment Length:	529	Identity:	148/529 - (27%)
Similarity:	266/529 - (50%)	Gaps:	63/529 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFAIAAALFYRWASANNDFFKDRGIAYEKPVLYFGNM----AGMFLRKRAMFDIVCDLYTKGGSK 68
            |..:...|.|.:....:.|||..||...:|..:||..    .|.|     .||:.|       :|
Zfish    13 LVVLVLTLLYMYGVWPHGFFKKLGIPGPRPWPFFGTFLSYTKGFF-----NFDMEC-------AK 65

  Fly    69 KF---FGIFEQRQPLLMVRDPDLIKQITIKD-FDHFINHRNVFATSSDDDPHDMSNLFGSSLFSM 129
            |:   :||::.|.|:|||.|.::||.|.:|: :..|.|.|.:..        |::......:.::
Zfish    66 KYGKVWGIYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREINV--------DLAGPLADGITAV 122

  Fly   130 RDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVI 194
            :|.|||.:|.||||.||..:::::|.:....|...:..:::.|   .|..:.:|:....::.||:
Zfish   123 KDERWKRIRGTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKGD---HEQPVKIKEVMASYSLDVV 184

  Fly   195 ASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFML--FFALKGLNKILKVELFDRKSTQYF 257
            .|:||.:.::|..:.::.|....|....|........:|  |.::..|...:.:.:|.:.:..:|
Zfish   185 TSSAFSVDIDSINNPDDPFVTNIKNFLKFNLFGLFVLLLTVFPSIANLLGKMGLSMFSKPTVDFF 249

  Fly   258 VRLVLDAMKYRQEH--NIVRPDMINMLMEARGIIQTE--------KTKASAVREWSDRDIVAQCF 312
            .:.:   .|.::||  :..|.|...::      ||.|        .|.....:..:|.:|::|.|
Zfish   250 YKAL---RKIKEEHKDSNGRVDFFRLM------IQNEIPDDQVKDTTSEQPEKGLTDHEILSQSF 305

  Fly   313 VFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLE-GKELTYEAIMGMKYLDQVVNE 376
            :|...|:||::..:.|..:.|..|.|..::|   |:::|::.. ...::|:|:|.:.||:..:||
Zfish   306 IFIMGGYETTSTTLTFLLYNLAINPDCLEKL---VEKIDKNFPLDTPISYDALMKIDYLEMSINE 367

  Fly   377 VLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDEN 441
            .:|..|.|..::|.|.|  |.:::|  :.:.|..:|.:||...::||:.:::|.:|.|||||.||
Zfish   368 SMRLLPTAPRLERVCKK--TVEMNG--ITIPKDTMITIPTYVLNQDPQLWDSPHEFRPERFSPEN 428

  Fly   442 KESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKG 506
            |.....:.:.|||||.|||||.|:||:..|.::..||:::.....|::.||||| ...||  ||.
Zfish   429 KSEFLQYAFMPFGLGPRNCIGMRYALMIVKLLVVKLLQNFSVETCKETQIPLEL-NPVFQ--PKV 490

  Fly   507 GFWIKLVQR 515
            ...:||..|
Zfish   491 PITLKLTPR 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	137/494 (28%)
cyp3c2	XP_021330384.1	p450	38..496	CDD:306555	137/499 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910