DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9f2 and Cyp6d4

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_651082.1	Gene:	Cyp6d4 / 42682	FlyBaseID:	FBgn0039006	Length:	515	Species:	Drosophila melanogaster

Alignment Length:	526	Identity:	155/526 - (29%)
Similarity:	274/526 - (52%)	Gaps:	33/526 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FALFAIAAAL-----FYRWASANNDFFKDRGIAYEK-PVLYFGNMAGMFLRKRAMFDIVCDLYTK 64
            |:|..:|..|     ||  ...:.::::.||..:|| ..:.||.:..::.::::|...:.|:|.|
  Fly     2 FSLILLAVTLLTLAWFY--LKRHYEYWERRGFPFEKHSGIPFGCLDSVWRQEKSMGLAIYDVYVK 64

  Fly    65 GGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSM 129
             ..::..||:...:|.:::||.||.:::..:||..| :.|.|: ...:.||      ..:::||:
  Fly    65 -SKERVLGIYLLFRPAVLIRDADLARRVLAQDFASF-HDRGVY-VDEERDP------LSANIFSL 120

  Fly   130 RDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVI 194
            |...|:.||..|||.||..|::.||.....:..:.|..|:::.......|:|:|.....:..|:|
  Fly   121 RGQSWRSMRHMLSPCFTSGKLKSMFSTSEDIGDKMVAHLQKELPEEGFKEVDIKKVMQNYAIDII 185

  Fly   195 ASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVR 259
            |||.|||.||||::.:|.|.::...........:|..|:.|.:..:.:.|....|........::
  Fly   186 ASTIFGLDVNSFENPDNKFRKLVSLARANNRFNAMFGMMIFLVPSIAQFLFRIGFKNPVGLAMLQ 250

  Fly   260 LVLDAMKYRQEHNIVRPDMINMLMEAR--GIIQTEKTKASAVREWSD--------RDIVAQCFVF 314
            :|.:.::||::|.|||.|::.:|::.|  |.|.....|:.::::..|        ..|.||.|:|
  Fly   251 IVKETVEYREKHGIVRKDLLQLLIQLRNTGKIDENDEKSFSIQKTPDGHIKTISLEAITAQAFIF 315

  Fly   315 FFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLR 379
            :.||.||:.....||.:||.:..::.:||.:||.:.....:|| :||:::..|::||..|.|.:|
  Fly   316 YIAGQETTGSTAAFTIYELAQYPELLKRLQDEVDETLAKNDGK-ITYDSLNKMEFLDLCVQETIR 379

  Fly   380 KWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKES 444
            |:|....::|||.:|.|  |......:.||..:.:...|.|.|.:||.:|..:||||||:|:: :
  Fly   380 KYPGLPILNRECTQDYT--VPDTNHVIPKGTPVVISLYGIHHDAEYFPDPETYDPERFSEESR-N 441

  Fly   445 IQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFW 509
            ..|..:.|||.|.|.||..|...:.:|..|..:|:::......:|.|..|  .||..|.||.|..
  Fly   442 YNPTAFMPFGEGPRICIAQRMGRINSKLAIIKILQNFNVEVMSRSEIEFE--NSGIALIPKHGVR 504

  Fly   510 IKLVQR 515
            ::|.:|
  Fly   505 VRLSKR 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	144/484 (30%)
Cyp6d4	NP_651082.1	p450	58..500	CDD:278495	137/456 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461149
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900