DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9f2 and Cyp6d2

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_611698.1	Gene:	Cyp6d2 / 37594	FlyBaseID:	FBgn0034756	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	147/521 - (28%)
Similarity:	259/521 - (49%)	Gaps:	42/521 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LWEFFALFAIAAALFYRWASANNDFFKDRGIAYEKPVLYFGNMAGMFLRKRAMFDIVCDLYTKGG 66
            :|... |..:.|.|.||:...:...::..|:..|...:.||.|..:..::|::...:.|:|.: .
  Fly     1 MWTIL-LTILIAGLLYRYVKRHYTHWQRLGVDEEPAKIPFGVMDTVMKQERSLGMALADIYAR-H 63

  Fly    67 SKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRD 131
            ..|..||:...:..:::||..|.:||...||..| :.|.|: ...|.||      ..::||::|.
  Fly    64 EGKIVGIYMLNKRSILIRDAQLARQIMTSDFASF-HDRGVY-VDEDKDP------LSANLFNLRG 120

  Fly   132 ARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIAS 196
            |.|:::|..|:|:|:..|::.||..::.|..:.|..|  :.:..|.:|:::||..|.:..|:|.|
  Fly   121 ASWRNLRQKLTPSFSSGKIKGMFGTIDDVGDKLVQHL--EGALDQSDEVEIKDVMTTYAVDIIGS 183

  Fly   197 TAFGLQVNSFKDRENTFYQMGKKLT-TFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVRL 260
            ..|||:::||::.:|.|.::....: ..:.|..:..|..|....:.|::....::.:.......:
  Fly   184 VIFGLEIDSFRNPKNEFREISSSTSRDESLLLKIHNMSMFICPPIAKLMNRLGYESRILTSLRDM 248

  Fly   261 VLDAMKYRQEHNIVRPDMINMLMEARGI---------IQTEKTKASAVREWSDRDIVAQCFVFFF 316
            :...:::|:|||:||.||:.:|:..|..         :...:|....::..|...|.||.|:|:.
  Fly   249 MKRTIEFREEHNVVRKDMLQLLIRLRNTGKIGEDDDQVWDMETAQEQLKSMSIEKIAAQAFLFYV 313

  Fly   317 AGFETSAVLMCFTAHELMENQDVQQRLYEEVQQV--DQDLEGKE-LTYEAIMGMKYLDQVVNEVL 378
            ||.|::|....||.:||....::.:...|||..|  ..:|:.|: .||||:..:|:||..:.|.:
  Fly   314 AGSESTAAASAFTLYELSMYPELLKEAQEEVDAVLMKHNLKPKDRFTYEAVQDLKFLDICIMETI 378

  Fly   379 RKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKE 443
            ||:|....::|||.:|  :.|.|....:.||..|.:...|..|||.||.||..:||.|| |.|..
  Fly   379 RKYPGLPFLNRECTED--YPVPGTNHIIAKGTPILISLFGMQRDPVYFPNPNGYDPHRF-DSNNM 440

  Fly   444 SIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLK------------DYRF--APAKKSCIPLE 494
            :.....|.|||.|.|:||..|...:.:|..:..:|.            ::||  ||...:..||:
  Fly   441 NYDQAAYMPFGEGPRHCIALRMGKVNSKVAVAKILANFDLVQSPRKEVEFRFDAAPVLVTKEPLK 505

  Fly   495 L 495
            |
  Fly   506 L 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	139/487 (29%)
Cyp6d2	NP_611698.1	p450	65..506	CDD:278495	132/453 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461137
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I1773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900