DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9f2 and Cyp6g1

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001286335.1	Gene:	Cyp6g1 / 36316	FlyBaseID:	FBgn0025454	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	524	Identity:	171/524 - (32%)
Similarity:	283/524 - (54%)	Gaps:	37/524 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFAIAAAL--FYRWASANNDFFKDRGIAYEKPVLYFGNMAGMFLRKRAMFDIVCDLYTKGGSK-- 68
            ||.:.|||  .|.|...|:.:::.:||.|..|....||...:|..:.:....:.::|.....|
  Fly     7 LFVVVAALVALYTWFQRNHSYWQRKGIPYIPPTPIIGNTKVVFKMENSFGMHLSEIYNDPRLKDE 71

  Fly    69 KFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDAR 133
            ...||:...:|.|::||.:|||.|.||||:.|   .|.:|..   |||. ..|..::||.:|||.
  Fly    72 AVVGIYSMNKPGLIIRDIELIKSILIKDFNRF---HNRYARC---DPHG-DPLGYNNLFFVRDAH 129

  Fly   134 WKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENE----LDMKDYCTRFTNDVI 194
            ||.:|:.|:|.||..|::||:.||.::.|:....|::   |.::|.    .::|:.|.:|:.|.|
  Fly   130 WKGIRTKLTPVFTSGKVKQMYTLMQEIGKDLELALQR---RGEKNSGSFITEIKEICAQFSTDSI 191

  Fly   195 ASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVR 259
            |:.|||::.||.::....|...|:|:.|||..::..|.:.|.|..|..:::::.|....:.:...
  Fly   192 ATIAFGIRANSLENPNAEFRNYGRKMFTFTVARAKDFFVAFFLPKLVSLMRIQFFTADFSHFMRS 256

  Fly   260 LVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRD-IVAQCFVFFFAGFETSA 323
            .:...|:.|:...::|.|:|::|:..|.....|.:|....:   ::| :|||..|||.||||||:
  Fly   257 TIGHVMEERERSGLLRNDLIDVLVSLRKEAAAEPSKPHYAK---NQDFLVAQAGVFFTAGFETSS 318

  Fly   324 VLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVD 388
            ..|.|..:|:.::.::|:||.:|:.:...: .|..|:||.|..::||..||:||||.:|....:|
  Fly   319 STMSFALYEMAKHPEMQKRLRDEINEALVE-GGGSLSYEKIQSLEYLAMVVDEVLRMYPVLPFLD 382

  Fly   389 RECNKDITFDVDGQ---------KVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKES 444
            ||..     .|:||         ...::.|..:::|....|.||||:.||.:|||||||..|:::
  Fly   383 REYE-----SVEGQPDLSLKPFYDYTLENGTPVFIPIYALHHDPKYWTNPSQFDPERFSPANRKN 442

  Fly   445 IQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFW 509
            |....|.|||.|..||||||..||::|..:..|||::.....:.:...::....||.|...||..
  Fly   443 IVAMAYQPFGSGPHNCIGSRIGLLQSKLGLVSLLKNHSVRNCEATMKDMKFDPKGFVLQADGGIH 507

  Fly   510 IKLV 513
            :::|
  Fly   508 LEIV 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	159/489 (33%)
Cyp6g1	NP_001286335.1	p450	56..508	CDD:278495	155/470 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461041
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	11	10.800