DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9f2 and Cyp4ad1

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_610380.1	Gene:	Cyp4ad1 / 35821	FlyBaseID:	FBgn0033292	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	100/460 - (21%)
Similarity:	186/460 - (40%)	Gaps:	88/460 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 DPHDMSNLFGSS-------------------LFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQ 159
            ||.::.|:..||                   |.:...|||...:...:|||..|.:....:::::
  Fly    87 DPAEIQNILSSSSLLYKEHLYSFLRPWLGDGLLTSSGARWLKHQKLYAPAFERSAIEGYLRVVHR 151

  Fly   160 VAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFT 224
            ...:.|.  |.|.....:...|.::...:.|.|::...|.|...:|.....:..:...|.|.  .
  Fly   152 TGGQFVQ--KLDVLSDTQEVFDAQELVAKCTLDIVCENATGQDSSSLNGETSDLHGAIKDLC--D 212

  Fly   225 FLQSMKFMLFFALKGLNKILKVELFDR--KSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEAR- 286
            .:|...|.:            |:.||.  :.|.|:       ||.|:..:::|.::..::.:.|
  Fly   213 VVQERTFSI------------VKRFDALFRLTSYY-------MKQRRALSLLRSELNRIISQRRH 258

  Fly   287 -------------------GIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMCFTAHE 332
                               .::.|.|.....::|   |:|:.:...|.|.|.:..|..:.||.:.
  Fly   259 QLAAENTCQQGQPINKPFLDVLLTAKLDGKVLKE---REIIEEVSTFIFTGHDPIAAAISFTLYT 320

  Fly   333 LMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITF 397
            |..:.::||:..||.:::..:....|.....:..|.||:.::.|.||.:|:...:.|.....|
  Fly   321 LSRHSEIQQKAAEEQRRIFGENFAGEADLARLDQMHYLELIIRETLRLYPSVPLIARTNRNPI-- 383

  Fly   398 DVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSD-ENKESIQPFTYFPFGLGQRNCI 461
            |::|.||......::.|...|::.  |||::|..|.||||.: .....|:.|...||..|.|.||
  Fly   384 DINGTKVAKCTTVIMCLIAMGYNE--KYFDDPCTFRPERFENPTGNVGIEAFKSVPFSAGPRRCI 446

  Fly   462 GSRFALLEAKAVIYYLLKDYRFAPA------------KKSCIPLE----LITSGFQLSPKGGFWI 510
            ..:||:.:.||::..||:.:...||            ::.|:|..    ::.....|..:.|..|
  Fly   447 AEKFAMYQMKALLSQLLRRFEILPAVDGLPPGINDHSREDCVPQSEYDPVLNIRVTLKSENGIQI 511

  Fly   511 KLVQR 515
            :|.:|
  Fly   512 RLRKR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	97/453 (21%)
Cyp4ad1	NP_610380.1	p450	36..470	CDD:278495	91/412 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900