DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9f2 and Cyp310a1

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_609891.1	Gene:	Cyp310a1 / 35115	FlyBaseID:	FBgn0032693	Length:	492	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	114/546 - (20%)
Similarity:	235/546 - (43%)	Gaps:	106/546 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FFALFAIAAALFYRWASANNDFFKDRGIAYEKPVLYFGNMAGMFLRKRAMFDIVCDLYTKGGSKK 69
            :.|:|.....::..|        :.||...||..:.:..:...:.|:....:.:|:.| :.|..:
  Fly    10 YSAVFLSVRHIYSHW--------RRRGFPSEKAGITWSFLQKAYRREFRHVEAICEAY-QSGKDR 65

  Fly    70 FFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMRDARW 134
            ..||:...:|:|:||:.:|.:.|..:...||                             .:.:|
  Fly    66 LLGIYCFFRPVLLVRNVELAQTILQQSNGHF-----------------------------SELKW 101

  Fly   135 K--------DMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTN 191
            .        ::...|:|.|...::.:||..:.:|....:..|.....:....|:|::.....::.
  Fly   102 DYISGYRRFNLLEKLAPMFGTKRLSEMFGQVQKVGDHLIHHLLDRQGQGCPQEVDIQQKLRVYSV 166

  Fly   192 DVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILKVELFDRKSTQY 256
            ::||:..:||.:|:|:..::.       ||:: ...|...:..|.|..|.:        :.|..|
  Fly   167 NIIANLIYGLDINNFEHEDHI-------LTSY-LSHSQASIQSFTLGRLPQ--------KSSYTY 215

  Fly   257 FVR-LVLDAMKYRQEHNIVRPDMINMLMEAR--GIIQTEKTKASAVREWSDRDI-------VAQC 311
            .:| |:..:::.|::|.::|.|::.:|:..|  ..:..:|.:...:.: :|:.:       ||:.
  Fly   216 RLRDLIKQSVELREDHGLIRKDILQLLVRFRNGNEVSGDKWQLEPIND-ADKLLSIKRLAKVAED 279

  Fly   312 FVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYLDQVVNE 376
            .:  ....:..|..:.||..|:::...:.::|..|::::..  |..:|.:|.:.|::|:|..:.|
  Fly   280 LL--KVSLDAVASTVTFTLLEILQEPLIVEKLRAEIKELSN--ENGQLKFEELNGLRYMDMCLKE 340

  Fly   377 VLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERF---- 437
            .|||:|....::|.|.|  ::.:...|..:.:|..:.:|....|||.|||..|||:.|.||
  Fly   341 TLRKYPPLPIIERVCRK--SYSLPNSKFTIDEGKTLMVPLLAMHRDEKYFSEPMKYKPLRFLQTA 403

  Fly   438 ------SDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDY-------RFAPAKKS 489
                  .|:.|.::    :..||:|...|:|..||.|..|..:..||:::       :....|.|
  Fly   404 NDVGQCEDKTKSNV----FIGFGIGGSQCVGQNFAKLVIKVALIKLLQNFHLELDANQVKTLKVS 464

  Fly   490 CIPLELITSGFQLSPKGGFWIKLVQR 515
            ..|...|.:      |.|..:||.:|
  Fly   465 HRPAPFIHT------KDGLKVKLKRR 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	105/508 (21%)
Cyp310a1	NP_609891.1	p450	69..454	CDD:299894	93/440 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461155
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	7	6.850