DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9f2 and Cyp4a3

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_038965516.1	Gene:	Cyp4a3 / 298423	RGDID:	631356	Length:	511	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	112/467 - (23%)
Similarity:	193/467 - (41%)	Gaps:	88/467 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHDMSNLF-----------GSSLFSMRDARW 134
            :::.|||.:|.:.                 ...|| ..|.::           |..|..:...:|
  Rat    94 VLLYDPDYVKVVL-----------------GRSDP-KASGIYQFLAPWIVSGTGYGLLLLNGKKW 140

  Fly   135 KDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVD-CLKQDDSRVQENELDMKDYCTRFTNDVIASTA 198
            ......|:|||....::...::|.......:| ..|.||   |::.|::..|.:..|.|.:...|
  Rat   141 FQHWRMLTPAFHYGILKPYVKIMADSVSIMLDKWEKLDD---QDHPLEIFHYVSLMTLDTVMKCA 202

  Fly   199 FG------LQVNS------FKDREN-TFYQMGKKLTTFTFLQSMKF----------MLFFALKGL 240
            |.      |.|||      .:|..| ||:::.......:.:.:|..          :......|:
  Rat   203 FSHQGSVQLDVNSRSYTKAVEDLNNLTFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGV 267

  Fly   241 NKILKVELFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDR 305
            .|:.|.:|.:.:..|          |.|::.::   |.:::|:.|         |....:..||.
  Rat   268 IKMRKAQLQNEEELQ----------KARKKRHL---DFLDILLFA---------KMEDGKSLSDE 310

  Fly   306 DIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELTYEAIMGMKYL 370
            |:.|:...|.|.|.:|:|..:.:..:.|..:.:.|:|..||||.:..|  |..:|::.:..:.|.
  Rat   311 DLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGD--GTSVTWDHLDQISYT 373

  Fly   371 DQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPE 435
            ...:.|.||.:|...:|.||.:..:||. ||:  .:.||....:...|.|.:|.|:.||..|||.
  Rat   374 TMCIKEALRLYPPVPSVSRELSSPVTFP-DGR--SIPKGITTTILIYGLHHNPSYWPNPKVFDPS 435

  Fly   436 RFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGF 500
            |||.::..  ....|.||..|.|||||.:||:.|.|..:...|..:...| ..:.||:.:  :..
  Rat   436 RFSPDSPR--HSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP-DPTRIPVPM--ARL 495

  Fly   501 QLSPKGGFWIKL 512
            .|..|.|..::|
  Rat   496 VLKSKNGIHLRL 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	111/463 (24%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	111/464 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900