Protein Alignment Cyp9f2 and CYP4A22

DIOPT Version :9

• Sequence 1: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001010969.2
• Gene: CYP4A22 / 284541
• HGNCID: 20575
• Length: 519
• Species: Homo sapiens
• Alignment Length: 483
• Identity: 110/483 - (22%)
• Similarity: 186/483 - (38%)
• Gaps: 83/483 - (17%)

  Fly    55 FDIVCDLYTKGGSKKFFGIFEQRQPLLMVRDPDLIKQITIKDFDHFINHRNVFATSSDDDPHD-- 117
            |...|..:..||..:           :.:.|||.:|               |....||...|.
Human    82 FPSACPYWIWGGKVR-----------VQLYDPDYMK---------------VILGRSDPKSHGSY 120

  Fly   118 --MSNLFGSSLFSMRDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENEL 180
              ::...|..|..:....|...|..|:|||....::....||....:..:|  |.::...|::.|
Human   121 KFLAPRIGYGLLLLNGQTWFQHRRMLTPAFHNDILKPYVGLMADSVRVMLD--KWEELLGQDSPL 183

  Fly   181 DMKDYCTRFTNDVIASTAFGLQVNSFKDRENTFYQMGKKLTTFTFLQSMKFMLFFALKGLNKILK 245
            ::..:.:..|.|.|..:||..|.:...||.:..|        ...:..:..::|..::
Human   184 EVFQHVSLMTLDTIMKSAFSHQGSIQVDRNSQSY--------IQAISDLNSLVFCCMR------- 233

  Fly   246 VELFDRKSTQYFV----RLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVRE----- 301
             ..|....|.|.:    |....|.:...:|.    |.:..|.:|:...:.|..|....|.
Human   234 -NAFHENDTIYSLTSAGRWTHRACQLAHQHT----DQVIQLRKAQLQKEGELEKIKRKRHLDFLD 293

  Fly   302 ------------WSDRDIVAQCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDL 354
                        .||:|:.|:...|.|.|.:|:|..:.:..:.|..:...|:|..||:..:..|
Human   294 ILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGD- 357

  Fly   355 EGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGF 419
             |..:|:..:..|.|....:.|.||.:|....:.||.:..:||. ||:  .:.||.::.|...|.
Human   358 -GASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DGR--SLPKGIMVLLSIYGL 418

  Fly   420 HRDPKYFENPMKFDPERFSDENKESIQPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFA 484
            |.:||.:.|...|||.||:..:.:....|  .||..|.|||||.:||:.:.|......|..:...
Human   419 HHNPKVWPNLEVFDPSRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNQLKVARALTLLRFELL 481

  Fly   485 PAKKSCIPLELITSGFQLSPKGGFWIKL 512
            | ..:.||:.:  :...|..|.|..::|
Human   482 P-DPTRIPIPM--ARLVLKSKNGIHLRL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	109/479 (23%)
CYP4A22	NP_001010969.2	p450	52..505	CDD:278495	109/480 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900