Protein Alignment Cyp9f2 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_650189.1
• Gene: Cyp9f2 / 41520
• FlyBaseID: FBgn0038037
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 526
• Identity: 173/526 - (32%)
• Similarity: 285/526 - (54%)
• Gaps: 52/526 - (9%)

  Fly     4 EFFALFAIAAALFYRWASANNDFFKDRGIAYEKPVLYFGNMAG--MFLRKRAMFDIVCDLYTKGG 66
            |.:.|.|:...|.|.:.:..:..||.:||...||:.:||.:..  |.|.|   ||:.|  :.|.|
  Rat    10 ETWVLLAVVLVLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGLWK---FDVEC--HKKYG 69

  Fly    67 SKKFFGIFEQRQPLLMVRDPDLIKQITIKD-FDHFINHRNVFATSSDDDPHDMSNLFGSSLFSMR 130
              |.:|:|:.:.||..:.|.::||.:.:|: |..|.|.|       |..|   ..:.|.::...:
  Rat    70 --KIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRR-------DFGP---VGIMGKAISVSK 122

  Fly   131 DARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVIA 195
            |..||..|:.|||.||..::::||.::.|.....|..|:|:..:    .:.:|:....::.|||.
  Rat   123 DEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEKGK----PVPVKEVFGAYSMDVIT 183

  Fly   196 STAFGLQVNSFKDRENTFYQMGKKLTTFTFLQS--MKFMLFFALKGLNKILKVELFDRKSTQYFV 258
            ||:||:.|:|..:.::.|.:..|||....|...  :..:||..|..:.::|.:.:|.:.|.::|.
  Rat   184 STSFGVNVDSLNNPKDPFVEKAKKLLRIDFFDPLFLSVVLFPFLTPVYEMLNICMFPKDSIEFFK 248

  Fly   259 RLV-------LDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFF 316
            :.|       ||::   |:|   |.|.:.::|.|....:.:::..:.    ||.:|.||..:|.|
  Rat   249 KFVYRMKETRLDSV---QKH---RVDFLQLMMNAHNDSKDKESHTAL----SDMEITAQSIIFIF 303

  Fly   317 AGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGK-ELTYEAIMGMKYLDQVVNEVLRK 380
            ||:|.::..:.|..|.|..:.|.|::|.||   :|:.|..| ..||:.:|.|:|||.|:||.||.
  Rat   304 AGYEPTSSTLSFVLHSLATHPDTQKKLQEE---IDRALPNKAPPTYDTVMEMEYLDMVLNETLRL 365

  Fly   381 WPAAIAVDRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESI 445
            :|....::|.|.||:  :::|  |.:.||.|:.:|:...||||:::..|.:|.|||||.|||.||
  Rat   366 YPIGNRLERVCKKDV--EING--VFMPKGSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSI 426

  Fly   446 QPFTYFPFGLGQRNCIGSRFALLEAKAVIYYLLKDYRFAPAKKSCIPLELITSGFQLSPKGGFWI 510
            .|:.|.|||.|.|||||.||||:..|..:..:|:::.|.|.|::.|||:|...|. |.|.....:
  Rat   427 DPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGL-LQPTKPIIL 490

  Fly   511 KLVQRN 516
            |:|.|:
  Rat   491 KVVPRD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	CYP6-like	66..509	CDD:410679	150/453 (33%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	151/457 (33%)