DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp9f2 and Cyp4b1

DIOPT Version :9

Sequence 1:	NP_650189.1	Gene:	Cyp9f2 / 41520	FlyBaseID:	FBgn0038037	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_058695.2	Gene:	Cyp4b1 / 24307	RGDID:	2480	Length:	511	Species:	Rattus norvegicus

Alignment Length:	452	Identity:	113/452 - (25%)
Similarity:	181/452 - (40%)	Gaps:	70/452 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 FDHFINHRNVF------ATSSDDDPH--DMSNLF----GSSLFSMRDARWKDMRSTLSPAFTGSK 149
            |..|:...|::      |..|..||.  |:.:.|    |..|..:...:|...|..|:|.|....
  Rat    85 FGQFVGFLNIYEPDYAKAVYSRGDPKAADVYDFFLQWIGKGLLVLDGPKWFQHRKLLTPGFHYDV 149

  Fly   150 MRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCT--RFTNDVIASTAFGLQVNSFKDRENT 212
            ::....:..:..:..:|  |.:....:....|:  :|.  ....|.:....||...:....|:|:
  Rat   150 LKPYVAIFAESTRMMLD--KWEKKASENKSFDI--FCDVGHMALDTLMKCTFGKGDSGLGHRDNS 210

  Fly   213 FYQMGKKLTTF------TFLQSMKFMLFFALKGLNKILKVELFDRKSTQYFVRLVLDAMKYRQEH 271
            :|.....||..      :|.....|:.:....| .:.|:........|...:|....|::..:|.
  Rat   211 YYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHG-RRFLRACKIAHDHTDEVIRQRKAALQDEKER 274

  Fly   272 NIVRP----DMINMLMEAR---GIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFET-----SAV 324
            ..::.    |.:::|:..|   ||            :.||.::.|:...|.|.|.:|     |..
  Rat   275 KKIQQRRHLDFLDILLGVRDESGI------------KLSDAELRAEVDTFMFEGHDTTTSGISWF 327

  Fly   325 LMCFTAHELMENQDVQQRLYEEVQQV--DQDLEGKELTYEAIMGMKYLDQVVNEVLRKWPAAIAV 387
            |.|...:     .:.||...|||:.:  |||    ...::.:..|.||...:.|..|.:|....|
  Rat   328 LYCMALY-----PEHQQLCREEVRGILGDQD----SFQWDDLAKMTYLTMCMKECFRLYPPVPQV 383

  Fly   388 DRECNKDITFDVDGQKVEVKKGDVIWLPTCGFHRDPKYFENPMKFDPERFSDENKESIQPFTYFP 452
            .|:.||.:|| |||:.:..  |.:|.|.....||:...:.:|..|||.|||.||.....||.:.|
  Rat   384 YRQLNKPVTF-VDGRSLPA--GSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHPFAFMP 445

  Fly   453 FGLGQRNCIGSRFALLEAKAVIYYLLKDYRFA--PAKKSCIPLELITSGFQLSPKGGFWIKL 512
            |..|.|||||.:||:.|.|.|....|..:.|:  |:|......:||     |..|.|..:.|
  Rat   446 FSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPIKVPQLI-----LRSKNGIHLYL 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f2	NP_650189.1	p450	36..510	CDD:278495	112/448 (25%)
Cyp4b1	NP_058695.2	p450	47..500	CDD:278495	112/448 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900