Protein Alignment DNAlig3 and lig1

DIOPT Version :9

• Sequence 1: NP_650187.2
• Gene: DNAlig3 / 41518
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001119860.1
• Gene: lig1 / 556995
• ZFINID: ZDB-GENE-110404-2
• Length: 1058
• Species: Danio rerio
• Alignment Length: 669
• Identity: 165/669 - (24%)
• Similarity: 283/669 - (42%)
• Gaps: 120/669 - (17%)

  Fly    38 RICDEIAGESSYLKKAERLQRFFEKGSSGKGFKGDTVLWVQFLI-----PAANQRVYNLQNKALI 97
            |..::|..:|..||..|.|..|..   |......|.:|...:|.     ||.......:....|:
Zfish   436 RTFEKIEEDSGRLKNIETLSNFLR---SVILLSPDDLLCCVYLCLNQLGPAYQGLELGIGETVLM 497

  Fly    98 KLFSRIFNADQQQMHLDLEQDGD---VSETLRKH----FAASKKLKPQKQSKLYLQEVEEMLLHL 155
            |..::.......::..:.::.||   |:|:.|.:    ||.:........:||      :.:.|:
Zfish   498 KAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFAPANLTAGGVFNKL------KEIAHM 556

  Fly   156 VERTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDAF---------GPDAYPA 211
            ...:..:::.|:::.|.......:.|..:|.:...|||....:.:|.|.         |.:..||
Zfish   557 SGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLAALSQAVCLTPPGQEFPPA 621

  Fly   212 Y------QSSRDLVAIVEQFATKENKNYASSPVKKTKKTSSSAIQVM-----------------T 253
            .      .|:.:....:|:.|....:.|...|      ...:.|.|:                 .
Zfish   622 VLDAGKGMSTENRRVFLEEKALILKQTYCEMP------NYDAIIPVLLKEGIDELPNHCKLTPGV 680

  Fly   254 PISPMLASPCKSVEDAFKKSPTGLYS-EIKYDGERVQIH-KQGNDFKFFSRNLK------PVVDH 310
            |:.||||.|.|.|.:..|:.....:: |.||||||.||| .:..:.:.||||.:      |.:..
Zfish   681 PLRPMLAHPTKGVGEVMKRFDEASFTCEYKYDGERAQIHILENGEVRIFSRNQEDNTSKYPDIIS 745

  Fly   311 KIRALKKYIPQAFPGGGEMILDSEIILVDTDTGALLPFGSLGAHKKQ----TFANAAVCLFVFDC 371
            :|..:||...::      .:||||.:..|.:...:.||..|...|::    :.....||::.||.
Zfish   746 RIPQVKKESVRS------CVLDSEAVAWDREKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDL 804

  Fly   372 ILYDGEDLTQLPFRKRREILEQNIQPIKSHVQLSESEFLKTTRELAAMTARVLHANLEGVVLKS- 435
            :..:||.|.:.|..|||.:|.::....:.....:.|.....|..:|....:.:..:.||:::|:
Zfish   805 LYLNGESLVREPLSKRRALLRESFVEKEGEFVFARSLDADNTETIAEFLEQSVRDSCEGLMVKTL 869

  Fly   436 -PTSTYQPGKR--NWLKVKKDYLFDGKMADTADLVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLW 497
             ..:||:..||  ||||:||||| :| :.||.||.|:||:.|.||:.|....||:.|||.....:
Zfish   870 EKHATYEIAKRSHNWLKLKKDYL-EG-VGDTVDLCVIGAYLGKGKRAGGYGGFLLACYDEENEEF 932

  Fly   498 KTVTKVHSGLDDATNAEVHKSLIKLTERADANAIPS---WLLCSKSLVPDVLAKDPMKMPVWEIT 559
            ::|.|:.:|..| .:.|.|.:.:|      .:.:|.   :....:|..|||..:   .:.|||:.
Zfish   933 QSVCKIGTGFKD-EDLEQHYNFLK------EHILPKPRPYYRVDQSAEPDVWLE---AVQVWEVK 987

  Fly   560 GAEFTKSDAHTAS--------GISVRFPRITRRRSDKSAKEANDLAHLEDLFEASKSNVNVDLLL 616
            .|:.:.|..:.|:        |||:||||..|.|.||..::|...:.:.||::
Zfish   988 CADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATTGSQIADLYK------------ 1040

  Fly   617 ANCSKDETAMNNKTTPEKE 635
                |.:...|....|:.|
Zfish  1041 ----KQQQIQNQGDKPDLE 1055

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	33/173 (19%)
		dnl1	88..604	CDD:273147	147/581 (25%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	66/244 (27%)
		OBF_DNA_ligase_III	460..598	CDD:153436	46/148 (31%)
lig1	NP_001119860.1	PLN03113	301..1053	CDD:215584	163/665 (25%)
		DNA_ligase_A_N	430..601	CDD:282522	33/173 (19%)
		Adenylation_DNA_ligase_I_Euk	673..891	CDD:185710	64/223 (29%)
		OBF_DNA_ligase_I	896..1041	CDD:153438	48/170 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1793
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274264at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820