Protein Alignment DNAlig3 and lig-1

DIOPT Version :9

• Sequence 1: NP_650187.2
• Gene: DNAlig3 / 41518
• FlyBaseID: FBgn0286075
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_741625.2
• Gene: lig-1 / 179502
• WormBaseID: WBGene00002985
• Length: 773
• Species: Caenorhabditis elegans
• Alignment Length: 755
• Identity: 205/755 - (27%)
• Similarity: 342/755 - (45%)
• Gaps: 133/755 - (17%)

  Fly    35 TFRRICDEIAGESSYLKKAERLQRFFEKGSSGKGFKGDTV-----LWVQFLIPAANQRVYNLQNK 94
            |..:| :|::|:    ||.:.|.:||.|...   |..|.:     :.|..|.|:.......:...
 Worm    27 TLEKI-EELSGK----KKVDELAQFFTKVLD---FSPDDLTACVYMSVNQLGPSYEGLELGVAEN 83

  Fly    95 ALIKLFSRIFNADQQQMHLDLEQDGDV------SETLRKHFAASKKLK-PQKQSKLYLQEVEEML 152
            :|||..::.....:.::..||...||:      |.:.:|..|..|.|. |...:|  |.|:.:
 Worm    84 SLIKAVAKATGRTEGKIKEDLRAKGDLGTVAQQSRSNQKMLAVPKALTVPTVFNK--LTEIAK-- 144

  Fly   153 LHLVERTKEDEQTDLLQKLCSKATDLDLRTFIRLVKHDLRINARARHILDAFGPDAYPAYQSSR- 216
              |...:..:::.|.:..|......::.|..:|::...:||....:.:|.|.|    .|:..|:
 Worm   145 --LSGTSAMNKKVDAISALLIACQGIEARFLVRMLAGKMRIGLGEQSVLSALG----HAFTLSKI 203

  Fly   217 -------DLVAIVEQFATKENKN-YASSP-----------------VKKTKKTSSSAIQVMTPIS 256
                   |.:..::....|..|. |...|                 |:|.|.:..      .|:.
 Worm   204 TDQKVRGDKLDSLKDANVKRVKTAYCECPNYNRLIEVALTEGVEALVEKCKLSPG------IPLK 262

  Fly   257 PMLASPCKSVEDAFK--KSPTGLYSEIKYDGERVQIHKQ--GNDFKFFSRNLK------PVVDHK 311
            ||||.|.|.:::..:  ::.| :..|.||||||.||||:  |..| .:|||.:      |.:..|
 Worm   263 PMLAHPTKGIDEIMRRFRNQT-MTCEWKYDGERGQIHKREDGQIF-IYSRNQENNTTKYPDIIEK 325

  Fly   312 IRALKKYIPQAFPGGG--EMILDSEIILVDTDTGALLPFGSLGAHKKQTFAN---AAVCLFVFDC 371
            |        .:..|.|  ..|:|:|::.:| :.|.:|||..|...|::...:   ..|.:|:||.
 Worm   326 I--------SSCIGDGVTSFIVDAEVVAID-EAGLILPFQVLSTRKRKNATDDNGVKVVVFLFDL 381

  Fly   372 ILYDGEDLTQLPFRKRREILEQNIQPIKSHVQLSESEFLKTTRELAAMTARVLHANLEGVVLKS- 435
            :.::||.|.:.|.|||||:|..|.:.|......:.|.....|.|:.:.....:....||:::|:
 Worm   382 LYFNGEPLVRKPLRKRRELLRTNFKKIDGSFYFATSVDTNDTDEINSFFDEAVQNKCEGLMIKTL 446

  Fly   436 -PTSTYQPGKR--NWLKVKKDYLFDGKMADTADLVVLGAWYGSGKKGGTLSIFLMGCYDAFGRLW 497
             ..:||:..:|  :|||:||||: || :.||.||||:||:.|.||:.|....:|:|||:.....:
 Worm   447 DTEATYEISRRSHSWLKMKKDYV-DG-VGDTLDLVVMGAYSGVGKRTGVYGGYLLGCYNPTTEEY 509

  Fly   498 KTVTKVHSGLDDATNAEVHKSLIKLTERADANAIPSWLLCSKSLVPDVLAKDPMKMPVWEITGAE 562
            ::|.|:.:|..|...||.:|  |...::.|.:  ||:.....:|.||......:   |:|:..|:
 Worm   510 ESVCKIGTGFTDEDLAEQYK--ILQDKKIDKS--PSYYQFDHTLKPDDTFSPYL---VFEVKCAD 567

  Fly   563 FTKSDAHTAS--------GISVRFPRITRRRSDKSAKEANDLAHLEDLFEASKSNVNVDLLLANC 619
            .|.|..|.|:        |||:||||..|.|.||::.:|.....:.::::..::..|..:..|:.
 Worm   568 ITISPRHKAASGLTDDGKGISLRFPRFLRIRDDKNSDDATSSEQVLEMYKNQEAFANQKIEKADA 632

  Fly   620 SKDETAMNNKTTPEKEKKLNGNQSNGSKKLKRSNTGSDDEDGAPVLSK-RKESKAIRSLSPSQKG 683
            ..::.....|...|:|..:. |.|.||.|..            ||..: :||:.  :|:||.:..
 Worm   633 VDEDDEFEEKEDEEEELNMT-NVSEGSSKEN------------PVKEEIKKETP--KSVSPKKFE 682

  Fly   684 LKDFFKPSKEFKSVVKKEP--KEDE------GNIESTSSK 715
            .|...|.|...||.||..|  ||.|      .:|.|:|:|
 Worm   683 KKPPVKSSPVNKSPVKSSPIKKEAEKKKGPVASIFSSSTK 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAlig3	NP_650187.2	DNA_ligase_A_N	36..200	CDD:282522	37/175 (21%)
		dnl1	88..604	CDD:273147	158/575 (27%)
		Adenylation_DNA_ligase_III	242..454	CDD:185712	70/230 (30%)
		OBF_DNA_ligase_III	460..598	CDD:153436	49/145 (34%)
lig-1	NP_741625.2	DNA_ligase_A_N	20..190	CDD:282522	38/176 (22%)
		dnl1	77..617	CDD:273147	158/575 (27%)
		Adenylation_DNA_ligase_I_Euk	252..468	CDD:185710	71/232 (31%)
		OBF_DNA_ligase_I	473..618	CDD:153438	49/151 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274264at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920