DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stx12 and Syx7

DIOPT Version :9

Sequence 1:	XP_009292402.1	Gene:	stx12 / 415141	ZFINID:	ZDB-GENE-040625-11	Length:	267	Species:	Danio rerio
Sequence 2:	NP_730632.1	Gene:	Syx7 / 36173	FlyBaseID:	FBgn0267849	Length:	282	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	92/270 - (34%)
Similarity:	154/270 - (57%)	Gaps:	36/270 - (13%)

- Green bases have known domain annotations that are detailed below.

Zfish    14 DFSSLIQTCSSNIQKITLNTAQIKGLVNQLGTKLDTSGLRERLQYMQHHTNQLAKETNKHLKDLG 78
            ||..|.|..:::|||:..|.:.::.:||||.|..|:..|:::|..:..:||||..:||..:.:
  Fly    22 DFQRLAQIIATSIQKVQQNVSTMQRMVNQLNTPQDSPELKKQLHQIMTYTNQLVTDTNNQINE-- 84

Zfish    79 SISLPVSLSEQRQQKIQKDRLMNDFSAALNNFQAVQRQAAEKEKESVARAR----------AGSR 133
                 |...::|..|||:|||:::|:|||..||:|||:.|:.||.::.:||          ..||
  Fly    85 -----VDKCKERHLKIQRDRLVDEFTAALTAFQSVQRKTADIEKTALRQARGDSYNIARPPGSSR 144

Zfish   134 LSADDGGHDEQLVSFDNN-----------DDWGKTTTQTEDVAITEEDLELIKERETAIRQLESD 187
            ..:.:....:|    |||           .:..:..||.|:.|    ||:.::|:|..||:||::
  Fly   145 TGSSNSSASQQ----DNNSFFEDNFFNRKSNQQQMQTQMEEQA----DLQALEEQEQVIRELENN 201

Zfish   188 ILDVNQIFKDLAVMIHDQGEMIDSIEANVESAEVHVERGAEQLQRAAQYQQKSRKKICFLAVGLS 252
            |:.||:|:|.|..::::||..:||||:.||...:.|.:|.|.|::|:.|:.|.|||...|...||
  Fly   202 IVGVNEIYKKLGALVYEQGLTVDSIESQVEQTSIFVSQGTENLRKASSYRNKVRKKKLILVGILS 266

Zfish   253 IVVLIIGIVI 262
            .|:|.|.:::
  Fly   267 AVLLAIILIL 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stx12	XP_009292402.1	Syntaxin_2	23..125	CDD:291208	38/101 (38%)
stx12	XP_009292402.1	SNARE_syntaxin12	174..240	CDD:277229	26/65 (40%)
Syx7	NP_730632.1	Syntaxin_2	30..126	CDD:291208	38/102 (37%)
		COG5325	<97..276	CDD:227635	65/186 (35%)
		SNARE	188..247	CDD:304603	24/58 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585963
Domainoid	1	1.000	79	1.000	Domainoid score	I8601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	155	1.000	Inparanoid score	I4267
OMA	1	1.010	-	-		QHG53539
OrthoDB	1	1.010	-	-		D1204812at2759
OrthoFinder	1	1.000	-	-		FOG0000747
OrthoInspector	1	1.000	-	-		otm25038
orthoMCL	1	0.900	-	-		OOG6_102289
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3589
SonicParanoid	1	1.000	-	-		X633
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940