DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and PDGFC

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_057289.1	Gene:	PDGFC / 56034	HGNCID:	8801	Length:	345	Species:	Homo sapiens

Alignment Length:	181	Identity:	46/181 - (25%)
Similarity:	71/181 - (39%)	Gaps:	33/181 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   502 QYYGFRAEYRFLTNFGIMSGIQKEGCSFVYNSSERI-----SGLFHSPNFPGYYLENVVCNYYFY 561
            |..|.:||....:.|...|..::.|.....:  |||     :|..|||.||..|..|.|..:...
Human    16 QRQGTQAESNLSSKFQFSSNKEQNGVQDPQH--ERIITVSTNGSIHSPRFPHTYPRNTVLVWRLV 78

  Fly   562 GASDERVVLHFTYFDIEGIGSCDHQTAS-DYIEFSNFMSTDRKFSRYCGK--LPDFEMRSDGRFF 623
             |.:|.|.:..|:.:..|:...:..... |::|... .|......|:||.  :|..:: |.|...
Human    79 -AVEENVWIQLTFDERFGLEDPEDDICKYDFVEVEE-PSDGTILGRWCGSGTVPGKQI-SKGNQI 140

  Fly   624 RVTLHSNDRFVA-IGFRALYTF------ETVS-------------VNNSIT 654
            |:...|::.|.: .||...|..      |.||             :||:||
Human   141 RIRFVSDEYFPSEPGFCIHYNIVMPQFTEAVSPSVLPPSALPLDLLNNAIT 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001
		CUB	<414..512	CDD:238001	4/9 (44%)
		CUB	527..644	CDD:238001	32/125 (26%)
PDGFC	NP_057289.1	CUB	49..162	CDD:238001	30/115 (26%)
PDGFC	NP_057289.1	PDGF	248..340	CDD:238079
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910