DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and tll2l

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_001016661.1	Gene:	tll2l / 549415	XenbaseID:	XB-GENE-478930	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	351	Identity:	75/351 - (21%)
Similarity:	117/351 - (33%)	Gaps:	106/351 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FTVSHWP-------------LTMPAASLALGLTVVLLATGNGQSQQAVTNSKQSHFWLD------ 50
            ::|.|:|             :|.|..::.:|            .:..:||       ||
Frog   219 YSVMHYPRNAFSISPFLPTLITKPDPTIQIG------------QRYGLTN-------LDIAKINK 264

  Fly    51 ------CSCLHLSERNATQWGRLAINASHSLGAKNNCLMIFIAGMDDELVAFQLEQLQLRAGCL- 108
                  ||.| ||:.|.|.:.....:|...   ..||:.:.....:...|.|....||....|:
Frog   265 LYNCDVCSTL-LSDVNGTLFSPSYPSAYPD---NANCVWLIRIPSNQVSVQFIAFSLQTSQNCVS 325

  Fly   109 DSVDIFPYLREPVIENAT----LAADTFCQHSRERSATPIYSAGRLLGLRLRFQQPPTDLASWNL 169
            |.|.|:        :.||    :..|..|              |.||       .||. .||.||
Frog   326 DYVKIY--------DGATRSDPVLLDKAC--------------GSLL-------LPPI-TASSNL 360

  Fly   170 TLNASYRFLKRENFRTDGRLVPHSFCDFYFFASLSGEEANMGQGYFHSPQFPAHYPAHIKCAYKF 234
            .|   ..|:..|.....|      |...|...|..|...:.... |.||.:|..||....|.:..
Frog   361 ML---LEFVSNEGNTMTG------FEATYSTVSCGGTYTSQSNS-FSSPGYPVAYPPLTTCIWSI 415

  Fly   235 IGRPDTHVEILFEELQLPPVVSGG--CQLDALTLFDAESAHMNSVIDVI---CSSRPTRRLVSTG 294
            .......:.:...:::    |..|  |..|:||::|.    .|:...::   |.:......:|.|
Frog   416 YAPVGFKIVLTINKIE----VEYGLLCMYDSLTIYDG----YNTTAPILRCACGNTAVPNQISRG 472

  Fly   295 PDLLLEFNASSNRTAKGFRGKYKFVS 320
            ..:||.|::..:...|||:..|..:|
Frog   473 RSMLLVFSSDISVQKKGFQASYTLIS 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001	28/127 (22%)
		CUB	<414..512	CDD:238001
		CUB	527..644	CDD:238001
tll2l	NP_001016661.1	ZnMc_hatching_enzyme	86..268	CDD:239810	10/67 (15%)
		CUB	272..382	CDD:238001	36/152 (24%)
		CUB	385..495	CDD:238001	25/118 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910