DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34402 and CG42613

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_001247185.1	Gene:	CG42613 / 42269	FlyBaseID:	FBgn0261262	Length:	1188	Species:	Drosophila melanogaster

Alignment Length:	662	Identity:	157/662 - (23%)
Similarity:	262/662 - (39%)	Gaps:	157/662 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 SHSLGAKNNCLMIFIAGMDDELVAFQLEQLQLRA------------GCL-DSVDIFPYLREPVIE 123
            :||    ..||..|:|| ..:.|....:...||.            .|: :.:||:..::..  |
  Fly   297 NHS----RQCLYTFLAG-PGQRVEVVFKSFNLRGSPPDGSAVGELPSCVHEYMDIYSEVQSS--E 354

  Fly   124 NATLAADTF----CQHSRERSATPIYSAGRLLGLRLRF---QQPPTDLASWNLTLNASYRFLKRE 181
            .|.|....|    |.....|....:|.|     :.:.|   :...|||      ...::||:...
  Fly   355 PAELINSPFGGRYCGTIPPRRRISMYRA-----VAISFFSNKNVTTDL------FEGTFRFINAS 408

  Fly   182 NFRTDGRLVPHSFCDFYFFASLSGEEANMGQGYFHSPQFPAHYPAHIKCAYKFIGRPDTHVEILF 246
            .:.. |..:..|.|.:....|:|..:.    |...||.:|..||..:.|.|:|:|..:..|.:.|
  Fly   409 EYEI-GIPIAGSPCSYTITPSMSVNKT----GALISPTYPGAYPKDMSCTYQFLGESNQRVRLEF 468

  Fly   247 EELQLPPVVSGG--CQLDALTLFDAESAHMNSVIDVICSSRPTRRLVSTGPDLLLEF---NASSN 306
            .:..|   ..||  |..|.:.::|... :.:::|...|..:....|.|:...|.:.|   :.::|
  Fly   469 RDFDL---FFGGPHCPFDYVKVYDGPD-NSSALIGTYCGQQRNLVLYSSESSLFVHFYTLSRTAN 529

  Fly   307 RTAKGFRGKYKFVSNDLGVPNASVPPPAVLEAASVVVKQEKLQQEQASAAKENSLMSDVELSKPG 371
            ...:||:|.|:|                    :...||.:.:::......:.:
  Fly   530 TQNRGFKGIYEF--------------------SESFVKLDFIRENDGIHIRGS------------ 562

  Fly   372 RSFEQCKQTFDSRVNKSGIFDSNQLLLAKHALGGVVIGGSRVLQ------CRYEF----EAQAPE 426
                :|                :|.:|:|....|.|:..:....      |||..    :||..|
  Fly   563 ----EC----------------DQKILSKKESTGFVLSPNYPYPYIPKTVCRYFIYGMQDAQHLE 607

  Fly   427 RVQIRFHDFNVP-TEH--ENSTGCQPGDALHVVTELRGRYETQEL-------LCGAFLPKPLMSS 481
            ||::.|:.||:| .||  ::.:.|..|   ::...|:|: ||.:.       |||....: ::|.
  Fly   608 RVRLEFNAFNIPKVEHKDKSESNCTDG---YLKIYLKGQ-ETADAYDKFDYELCGNETQR-VISE 667

  Fly   482 GQQLHLQFVGKYPPTMTNKVQYYGFRAEYRFLTNFGIMSGIQKEG-CSFVYNSSERISGLFHSPN 545
            |.:|.:.|       .:.::|..||:.:|.|.|.:.|......:| |||.|.||.:..|..:||.
  Fly   668 GPRLAMVF-------SSGELQGRGFKGKYTFETEYKIPGTAAPDGTCSFTYVSSSKKRGELNSPR 725

  Fly   546 FPGYYLENVVCNYYFYGASDERVVLHFTYFDIE------------GIGSCDHQTASDYIEFSNFM 598
            :|..|..:..|:|.|...:||:|.:.|.:|.|:            |.|:|.......|:.:.:
  Fly   726 YPSNYPSDTNCSYLFLAEADEQVTIVFDHFKIKADNNANATAGAYGSGACFEDWLEMYVVYRD-- 788

  Fly   599 STDRKFSRYCGKLPDFEMRSD-GRF-FRVTLHSNDRFVAIGFRALYTFETVSVNNSITDLRDNAS 661
            :.||...||||:.....:.|. |.. .|:|||::...||.||:|.|.||  |..:...|...|.|
  Fly   789 NNDRLLGRYCGQTAPGPVESPRGAVGLRITLHTDQESVASGFKARYFFE--SAKSDAGDCGGNFS 851

  Fly   662 MQSFVSTASTQP 673
            .|.  |...|.|
  Fly   852 NQD--SGLITSP 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001	32/127 (25%)
		CUB	<414..512	CDD:238001	31/117 (26%)
		CUB	527..644	CDD:238001	42/130 (32%)
CG42613	NP_001247185.1	CUB	277..404	CDD:238001	25/124 (20%)
		CUB	421..541	CDD:238001	32/127 (25%)
		CUB	564..691	CDD:238001	37/154 (24%)
		CUB	707..836	CDD:238001	42/130 (32%)
		CUB	846..969	CDD:238001	6/18 (33%)
		LDLa	987..1022	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47537
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010