DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and nrp2a

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_998130.1	Gene:	nrp2a / 405901	ZFINID:	ZDB-GENE-040611-2	Length:	927	Species:	Danio rerio

Alignment Length:	478	Identity:	84/478 - (17%)
Similarity:	127/478 - (26%)	Gaps:	237/478 - (49%)

- Green bases have known domain annotations that are detailed below.

  Fly   197 FYFFASLSGEEAN--------MGQGYFHSPQFPAHYPAHIKCAYKFIGRPDTHVEILFEELQLPP 253
            |.|...:|.:|:.        .|.||..||.:|..||.|..|.:
Zfish    14 FCFVLKVSAKESETCGGHLDASGAGYITSPGYPLEYPPHQSCQW--------------------- 57

  Fly   254 VVSGGCQLDALTLFDAESAHMNSVIDVICSSRPTRRLVSTGPDLLLEFNASSNRTAKGFRGKYKF 318
                                      ||.:..|::|:|       |.||
Zfish    58 --------------------------VISAPEPSQRIV-------LNFN---------------- 73

  Fly   319 VSNDLGVPNASVPPPAVLEAASVVVKQEKLQQEQASAAKENSLMSDVELSKPGRSFEQCKQTFDS 383
                         |...||.
Zfish    74 -------------PHFELER--------------------------------------------- 80

  Fly   384 RVNKSGIFDSNQLLLAKHALGGVVIGGSRVLQCRYEFEAQAPERVQIRFHDFNVPTEHENSTGCQ 448
                                          |.|||:|       ::||
Zfish    81 ------------------------------LDCRYDF-------IEIR----------------- 91

  Fly   449 PGDALHVVTELRGRYETQELL---CGAFLPKPLMSSGQQLHLQFVGKYPPTMTNKVQYYGFRAEY 510
                       .|..|:.:||   |....|..::|||..:|::||..|..      |..||...|
Zfish    92 -----------DGNSESADLLGKHCSNIAPPAIISSGPFIHIKFVSDYAH------QGAGFSLRY 139

  Fly   511 RFLTNFGIMSGIQKEGCSFVYNSSERISGLFHSPNFPGYYLENVVCNYYFYGASDERVVLHFTYF 575
            .          |.|.|....:.:....:|:..||.||..|..|:.|::.........|.|.|..|
Zfish   140 E----------IFKTGAEHCFRNFSSPTGVIESPGFPDKYPHNLECSFIIIAPPQTEVTLTFQTF 194

  Fly   576 DIE------GIGSCDHQTASDYIE-FSNFMSTDRKFSRYCG-KLPDFEMRSDGRFFRVTLHSNDR 632
            |:|      |.|.|.:    |::: :...........|||| |:|. :::|......::.|::..
Zfish   195 DLENDPLLMGEGECKY----DWLDVWDGLPQVGPLIGRYCGSKIPP-KIQSSTGLLSLSFHTDMA 254

  Fly   633 FVAIGFRALYTFETVSVNNSITD 655
            ....||.|.|..    .:|.::|
Zfish   255 VAKDGFSARYNM----THNEVSD 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001	22/128 (17%)
		CUB	<414..512	CDD:238001	24/100 (24%)
		CUB	527..644	CDD:238001	30/124 (24%)
nrp2a	NP_998130.1	CUB	28..141	CDD:238001	45/321 (14%)
		CUB	149..264	CDD:238001	29/119 (24%)
		FA58C	282..426	CDD:238014
		FA58C	439..591	CDD:238014
		MAM	636..786	CDD:99706
		DUF3481	849..927	CDD:371830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910