DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and pcolce2b

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	NP_956754.1	Gene:	pcolce2b / 393432	ZFINID:	ZDB-GENE-040426-1177	Length:	413	Species:	Danio rerio

Alignment Length:	481	Identity:	94/481 - (19%)
Similarity:	149/481 - (30%)	Gaps:	193/481 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 LTLNASYRFLKRENFRTDGRLVPHSFCDFYFFASLSGEEANMG-QGYFHSPQFPAHYPAHIKCAY 232
            |.|:...:...|::|...|              :::||...:| |||      |..||.:.||.:
Zfish    12 LRLHVQAQSQSRQSFTCGG--------------NITGESGVIGSQGY------PGVYPPNTKCVW 56

  Fly   233 KFIGRPDTHVEIL-FEELQLPPVVSGGCQLDALTLFDAESAHMNSV-IDVICSSRPTRRLVSTGP 295
            : |..|:..|.:| |..|.|..  ...|:.|.:   |..|.|.|.. :...|.:.....||||..
Zfish    57 R-ITVPEGKVAVLTFRFLDLES--DNLCRYDYV---DVYSGHGNGQRLGRFCGTFRPGALVSTSN 115

  Fly   296 DLLLEFNASSNRTAKGFRGKYKFVSNDLGVPNASVPPPAVLEAASVVVKQEKLQQEQASAAKENS 360
            .:|::..:.:|....||...|                                     |||..|.
Zfish   116 KMLMQMVSDANTAGSGFLAVY-------------------------------------SAANPNE 143

  Fly   361 LMSDV---ELSKPGRSFEQCKQTFDSRVNKSGIFDSNQLLLAKHALGGVVIGGSRVLQCRYEFEA 422
            .....   .|.||..||:  ...:..|...:|:                        .|.:...|
Zfish   144 RGDQYCGGRLMKPSGSFK--TPNWPERDYPAGV------------------------TCSWHIVA 182

  Fly   423 QAPERVQIRFHDFNVPTEHEN---------STGCQPGDALHVVTELRGRYETQELLCGAFLPKPL 478
            ...:.::::|..|:|  |.:|         ..|.:..||..:     |:|      ||...|.|:
Zfish   183 PKNQIIEVKFEKFDV--ERDNYCRYDYVAIFNGGEINDAKRI-----GKY------CGDTPPAPV 234

  Fly   479 MSSGQQLHLQ-----------FVGKY------------------PPTMT-------------NKV 501
            .|.|.||.:|           |:|.|                  |||.|             .|.
Zfish   235 FSEGNQLFIQFLSDLSLTADGFIGHYKFRPKKFPSTTVPPTTTAPPTTTRPTPLKYSAALCQQKC 299

  Fly   502 QYYGFRAEYRFLTNFGIMSGIQKEGCSFVYNSSERISGLFHSPNFPGYYLEN------------- 553
            :..|....:...:|| :::|.       |..::.|...::.:.:....|.|.
Zfish   300 KRKGTPESHYCSSNF-VITGT-------VITATTRGGSMYATISIINVYKEGNLAIQQAGKTMST 356

  Fly   554 ---VVC----------NYYFYGASDE 566
               ::|          ||.|.|.:||
Zfish   357 KIVILCKKCPYVRRGLNYIFMGQADE 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001	34/125 (27%)
		CUB	<414..512	CDD:238001	30/148 (20%)
		CUB	527..644	CDD:238001	11/66 (17%)
pcolce2b	NP_956754.1	CUB	28..138	CDD:238001	35/172 (20%)
		CUB	149..260	CDD:278839	30/149 (20%)
		NTR_PCOLCE	290..413	CDD:239631	16/101 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5088
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4379
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.050