DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34402 and OVCH2

DIOPT Version :9

Sequence 1:	NP_001097756.1	Gene:	CG34402 / 41513	FlyBaseID:	FBgn0085431	Length:	695	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	323	Identity:	72/323 - (22%)
Similarity:	120/323 - (37%)	Gaps:	74/323 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   377 CKQTFDSRVNKS-----GIF-DSNQLL--LAKHALGG--------------VVIGGSRVLQCRYE 419
            |.:.:.:.|.||     ||| |.:::|  :.:|...|              |::.|:       |
Human   269 CGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQTGNRRKSSRAWCSEQDVIVSGA-------E 326

  Fly   420 FEAQAPERVQIRFHD-------FNVPTE--------HENSTGCQPGDALHVVTELR--GRYETQE 467
            .:...||.:.:.:..       ..||.|        |.:...|..........|.|  |::
Human   327 GKLHFPESLHLYYESKQRCVWTLLVPEEMHVLLSFSHLDVESCHHSYLSMYSLEDRPIGKF---- 387

  Fly   468 LLCGAFLPKPLMSSGQQLHLQFVGKYPPTMTNKVQYYGFRAEYRFL-TNFGIMSGIQKEGCSFVY 531
              ||..||..::.....|.|:||........      ||...|:.| .|:     |...|||::.
Human   388 --CGESLPSSILIGSNSLRLKFVSDATDNAA------GFNLTYKALKPNY-----IPDSGCSYLT 439

  Fly   532 NSSERISGLFHSPNFPGYYLENVVCNYYFYGASDERVVLHFTYFDIEGIGSCDHQTASDYIEFSN 596
            ...|  .||..|.|:|..|.:...|::.|..:....:.|.|...:||..|.|    .|||:...:
Human   440 VLFE--EGLIQSLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIEESGDC----TSDYVTVHS 498

  Fly   597 FMSTDRKFSRYCGKLPDFEMRSDGRFFRVTLHSNDRFVAIGFRALYTFETVSV----NNSITD 655
            .:...::.:|.||......:.|......::..|::.....||:|..:|...:|    |.||::
Human   499 DVERKKEIARLCGYDVPTPVLSPSSIMLISFQSDENGTCRGFQATVSFIPKAVYPDLNISISE 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34402	NP_001097756.1	CUB	195..318	CDD:238001
		CUB	<414..512	CDD:238001	22/114 (19%)
		CUB	527..644	CDD:238001	28/116 (24%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	9/28 (32%)
		Tryp_SPc	56..301	CDD:238113	9/31 (29%)
		CUB	320..424	CDD:238001	24/122 (20%)
		CUB	435..546	CDD:238001	28/116 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910